By Jason Napodano, CFA
We have reviewed twenty scientific papers in an attempt to better understand the mechanism of action, preclinical data, and the commercial potential for Amarantus Biosciences' (OTC:AMBS) Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF). Below is a review of those papers, in chronological order from the date they were first published.
Paper # 1 - Petrova PS, Raibekas A, Pevsner J, Vigo N, Anafi M, Moore MK, Peaire AE, Shridhar V, Smith DI, Kelly J, Durocher Y, Commissiong JW. (April 2003) MANF: A New Mesencephalic, Astrocyte-Derived Neurotrophic Factor with Selectivity for Dopaminergic Neurons. Journal of Molecular Neuroscience, Vol.20/2:173-187.
The Petrova et al. paper above was the first characterization we found on MANF. Petrova...