Congrats to the Dendreon (NASDAQ:DNDN) longs… really. I know what you're feeling. You held on for so long, you earned this gain. The happiness regarding the potential to see this game-changing-technology, and how it will benefit thousands of people… you're a part of it.
It's a good feeling, and you want to keep being a shareholder… I know.
But don’t forget the people in the shadows on this one. The minority want to see DNDN fail, and it is their mission to protect the status quo.
The best piece of info that I can give (this from a man that has lived through your very emotions): Sell a chunk of it NOW, or protect the vast majority of the gains via longer-term Puts (probably the Jan 2010 20 strike puts).
Congrats again, and I truly hope the treatment can get out to the people that need it the most. But please, put emotion aside and protect your gains.