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At the start of the new year, we highlighted the 50 best performing stocks of the 2000s. At the very top of the list was Medifast (NYSE:MED), which gained a whopping 16,209% during the decade. While MED was the best performing stock in the US last decade, it has gotten off to a very poor start this decade. As shown below, MED is already down 25% in 2010. Just today the stock was down $4.01 (-14.85%).

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Source: The Best Stock of the Last Decade Has a Rough Start to the New One