On January 6, 2014, Neurocrine Biosciences, Inc. (NBIX) announced results from the Phase 2b KINECT-2 study with small molecule VMAT2 inhibitor, NBI-98854, showed statistically significant and clinically meaningful reduction in tardive dyskinesia symptoms. The news is a pleasant surprise to Neurocrine investors after the mixed results of the KINECT-1 study in September 2013. The key differences between these two trials include dose titration and underlying disorder. Below we provide a quick background on the drug, a summary of the data from KINECT-2, a rehash of the KINECT-1 data, post some thoughts on what the future holds with respect to KINECT-3, outline timelines for moving NBI-98854 forward, and conclude with a valuation for the shares...
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