Jason Napodano, CFA
Research analyst, medium-term horizon, biotech, small-cap

MYOS Corp. Tackles Muscles Health

MYOS Corporation (NASDAQ:MYOS) is developing nutritional and therapeutic products aimed at maintaining and improving the health and performance of muscle tissue. One current target of the research being conducted by MYOS is the inhibition of myostatin, a powerful negative muscle regulatory protein.

Background on Myostatin

A 1997 article in the journal Nature first described the discovery of a novel member of the transforming growth factor-β (TGF-β) superfamily of growth and differentiation factors. This factor was expressed specifically in adult skeletal muscle and referred to as growth/differentiation factor-8 (GDF-8) (McPherron et al., 1997). The researchers created "knockout" mice, whereby they disrupted the expression of GDF-8 throughout the organism, with the resulting mice showing a large and widespread increase

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