Vertex Pharmaceuticals (VRTX) engages in the discovery, development, and commercialization of small molecule drugs for the treatment of serious diseases worldwide. Its product pipeline includes Telaprevir (VX-950), a Phase III clinical trial product for the treatment of hepatitis C virus (HCV) infection; VX-222, a Phase IIa clinical trial product targeting HCV infection; VX-770, a Phase III clinical trial candidate for the treatment of cystic fibrosis; and VX-809, a Phase IIa clinical trial product targeting cystic fibrosis.
The company's products also comprise VX-509, a Phase IIa clinical trial product for the treatment of rheumatoid arthritis; VX-765, a Phase IIa clinical trial product targeting epilepsy; and VX-759, a Phase I clinical trial product for the treatment of HCV infection. It has collaboration agreements with Janssen Pharmaceuticals, Mitsubishi Tanabe Pharma Corporation, Cystic Fibrosis Foundation Therapeutics Incorporated, Merck & Co (MRK) and GlaxoSmithKline (GSK). The company was founded in 1989 and is headquartered in Cambridge, Massachusetts.
Drug Pipeline
Telaprevir (VX-950), treatment of hepatitis C virus (HCV) infection.
VX-222, targeting HCV infection.
VX-770, treatment of cystic fibrosis.
VX-809, targeting cystic fibrosis.
VX-509, treatment of rheumatoid arthritis.
VX-765, targeting epilepsy.
VX-759, treatment of HCV infection.

VRTX has a real nice pipeline going for it. Some believe Vertex is an acquisition target for mega pharmas like Bristol-Meyers (BMY) and Pfizer (PFE), companies that seem to be seeking out smaller bio-pharmas with deep and impressive pipelines. However, with a market cap of 7.45 billion, it is hard to imagine a mega pharma would be willing to pay such a hefty price tag for Vertex.
| Fiscal Year |
| Fiscal Year Ends: | Dec 31 |
| Most Recent Quarter (mrq): | Sep 30, 2011 |
| Profitability | | Profit Margin: | -33.90% | | Operating Margin : | -18.85% | |
| Management Effectiveness | | Return on Assets : | -5.40% | | Return on Equity : | -47.41% | |
| Income Statement | | Revenue : | 912.81M | | Revenue Per Share : | 4.49 | | Qtrly Revenue Growth (yoy): | 2,670.30% | | Gross Profit : | 130.64M | | EBITDA 6: | -138.57M | | Net Income Avl to Common : | -309.45M | | Diluted EPS : | -1.52 | | Qtrly Earnings Growth (yoy): | N/A | |
| Balance Sheet | | Total Cash (mrq): | 658.68M | | Total Cash Per Share (mrq): | 3.16 | | Total Debt (mrq): | 498.42M | | Total Debt/Equity (mrq): | 68.20 | | Current Ratio (mrq): | 2.27 | | Book Value Per Share (mrq): | 2.78 | |
| Cash Flow Statement |
| Operating Cash Flow : | -526.03M |
| Levered Free Cash Flow : | -378.06M |
The current Vertex balance sheet does not look great in terms of profit generation and cash burn, but with a deep pipeline and plenty of cash on hand for larger phase 3 clinical funding, all Vertex needs is The FDA to approve a couple of their pipelined drugs to generate big revenue and turn huge profits in the future.
In my opinion, Vertex seems to have the technological know-how, so these drugs should see the market eventually. I really like their science and I strongly feel Vertex is engaged in very important work for the betterment of society with these drugs. I encourage potential investors to do the deeper due dilligence on all the phase clinical data, as I think most will like what they find.
I think for the very aggressive investor who is willing to buy and hold Vertex for 3 to 5 years, they could see a price appreciation of up to 5 times the current pps of $35.72 in this time frame. Numerous speculative biopharmas also make for very good swing trades, so consider looking at Vertex for this as well.
Disclosure: I have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours.