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As we enter the second half of 2012, below is a list of the best performing stocks in the Russell 3,000 so far this year. The average stock in the entire index is currently up 11.87% year to date. The 44 stocks below are all up more than 100% in 2012.

As shown, Threshold Pharmaceuticals (NASDAQ:THLD) is up the most of any stock with a YTD gain of 506.56%. Two other stocks are up more than 400% -- BioDelivery Sciences (NASDAQ:BDSI) and Arena Pharmaceuticals (NASDAQ:ARNA). A few other notables on the list of 2012's biggest winners include US Airways (LCC), 3D Systems (NYSE:DDD) and Hovnanian (NYSE:HOV), but most stocks on the list are likely unknown to the bulk of investors. Have a look through the names over the weekend if you have a chance.

Source: Best Performing Stocks At 2012's Midpoint