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Kirk Lindstrom has an engineering degree from the University of California, Berkeley. Following 20 years of research and development as a scientist and engineer at Hewlett Packard, Kirk turned his attention to investments where he edits "Kirk Lindstrom's Investment Letter," that... More
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  • Antigenics Soars on Oncophage Kidney Cancer Survival Data

    One of my "explore portfolio" stocks, Antigenics Inc., (AGEN Charts) surged recently on positive survival data for its cancer drug Oncophage® (vitespen).

    Charts don't show on instablogs with cut and paste so read the full article at:

    Antigenics Surges on Oncophage Kidney Cancer Survival Data

    As of today's close at $1.53, AGEN is up 219% YTD.
    Click chart courtesy of stockcharts.com for full size image here

    Interim survival data showed that patients with kidney cancer at intermediate risk of disease recurrence demonstrated an approximately 46% lower risk of death when treated with Oncophage® compared to the control group. Press Release

    Adding to the good news, survival comes without significant "toxicities"
    “Demonstration of an overall survival benefit remains the gold standard, and these interim results show that Oncophage has a real promise of improving survival in patients with earlier-stage disease for whom current prognosis remains poor,” said Dr. Wood. “Based on these results, Oncophage offers these patients a potential treatment that extends survival without significant toxicities.”
    About Oncophage:
    In April 2008, Oncophage was approved in Russia for the adjuvant treatment of kidney cancer patients at intermediate-risk for disease recurrence. Pre-commercial launch activities are ongoing. In October 2008, Antigenics submitted a marketing authorization application to the European Medicines Agency (EMEA) requesting conditional approval for Oncophage in earlier-stage, localized renal cell carcinoma.

    Derived from each individual’s tumor, Oncophage contains the ‘antigenic fingerprint’ of the patient’s particular cancer and is designed to reprogram the body’s immune system to target only cancer cells bearing this fingerprint. Oncophage is intended to leave healthy tissue unaffected and limit the debilitating side effects typically associated with traditional cancer treatments such as chemotherapy and radiation therapy. Oncophage has been studied in Phase 3 clinical trials for the treatment of kidney cancer and metastatic melanoma and is currently being investigated in a Phase 2 trial in recurrent glioma.

    Oncophage received fast track and orphan drug designations from the US Food and Drug Administration (FDA) for both kidney cancer and metastatic melanoma as well as orphan drug designation from the EMEA for kidney cancer. In 2009, Oncophage also received orphan drug designations from the FDA and EMEA for glioma.

    In April 2009, the World Vaccine Congress named Oncophage as the best therapeutic vaccine.
    Even if you do not own the stock, you have to hope the company is successful as the treatment has the potential to work with almost all cancers.

    Disclaimer: I own and cover AGEN in "Kirk Lindstrom's Investment Letter" with my last buy below the current price as of this writing. I may sell or buy more shares without notice here but I will update my subscribers of any changes.

    Doubled Money in a Down Market!

     

    Since 12/31/98 "Kirk's Newsletter Explore Portfolio" is UP 111% (over a double!) vs. the S&P500 DOWN 9% vs. NASDAQ down 16% vs. Warren Buffett's Berkshire Hathaway (BRKA) up 31% (All through 6/2/09)

    As of June 2, 2009, "Kirk's Newsletter Explore Portfolio" is up 8.4% YTD
    vs. DJIA DOWN 0.4%    (More Info & FREE Sample Issue)

    Jun 03 9:25 AM | Link | Comment!
  • Cisco Systems Stock is Testing Key Support Level

    Originally poste at "Cisco Stock Testing Key Support Level" with charts and graphs that have been a problem getting to post here.

    Cisco Systems (more CSCO charts) is testing its 200-day moving average (DMA) from above as the bulls and bears do battle over this key level. During bull markets, the 200 DMA is support while in a bear market, the 200-DMA is resistance.

    Click chart courtesy of stockcharts.com for full size image
    See article for chart

    Quite often, after resistance changes to support, there is a test from above of the new support level before the stock takes off for big gains.

    KEY bull/bear battle:

    • If bullish, buy with a stop-loss below the 200 DMA for what you are willing to lose. If this is a new bull market, then the 200-DMA should become support rather than resistance.
       
    • If bearish, this is a good place to unload before your expected decline to new lows just as the rally above the 200DMA in 2001 was a good place to get out above $20 before falling to $8 and change in 2002.

    Click chart courtesy of stockcharts.com for full size image
    See article for chart

    I've traded Cisco in the past but I don't have a current position. I prefer other stocks (listed in Kirk Lindstrom's Investment Letter Explore Portfolio.) Also, I did so much buying of other stocks when the market was lower, that now I am looking to take some more profits rather than add more stocks.

    Remember, the S&P500 (S&P500 charts) is up in the 900s from just recently being in the 600s. A correction could come out of nowhere at any time.

    Click chart courtesy of stockcharts.com for full size image
    See article for chart

    The bears think this is a bear market rally before the market makes new lows. By taking some profits on what we bought at much lower levels, we have funds to buy again if the market corrects.

    More information:

    Doubled Money in a Down Market!

    Since 12/31/98 "Kirk's Newsletter Explore Portfolio" is UP 107% (over a double!) vs. the S&P500 DOWN 11% vs. NASDAQ down 21% vs. Warren Buffett's Berkshire Hathaway (BRKA) up "only" 35% (All through 5/8/09) (More Info)

    HURRY! Subscribe NOW and get the May 2009 Issue of "Kirk Lindstrom's Investment Newsletter" for FREE! !

    YTD "Kirk's Newsletter Explore Portfolio" is UP 6.3% vs. the S&P500 UP 2.4% vs. DJIA down 2.6%

    Tags: CSCO, SPY, S P500
    May 08 12:39 PM | Link | Comment!
  • Swine Flu Cure: Flu-Cide from NanoViricides is Designed to Destroy Influenza A Viruses
    Swine Flu Cure: NanoViricides Flu-Cide Drug Designed to Destroy Influenza A Viruses
    NanoViricides (more NNVC Charts) surges on swine flu scare. NanoViricides"Flu... is a cure, not a vaccine.
     
    NanoViricides stock did quite well a few years ago during a bird-flu scare. I bought my first shares at $1.01 and took profits at $2.80. See below for long-term chart showing how it surged t0 $3.75 during the 2006 Bird Flu scare.
     
    After NNVC came back to Earth after that scare, I started accumulating shares in "Kirk Lindstrom's Investment Letter Explore" (FREE Sample Issue) and personal portfolios to load up for the next run.


    Below is today's press release from NanoViricides:


    PRESS RELEASE: NanoViricides, Inc. Says Flu-Cide Drug Designed to Destroy All Influenza A Viruses Including Swine and Bird Flu

    Already shown to be effective against diverse influenza subtypes such as H1N1 and different clades of H5N1

    On Monday April 27, 2009, 7:00 am EDT

    WEST HAVEN, Conn.--(BUSINESS WIRE)--NanoViricides, Inc. (OTC BB: NNVC.OB) (the "Company"), announced that it is developing FluCide(™), its flagship anti-influenza drug candidate, to work against all influenza types and subtypes. FluCide has been shown to be effective against both common influenza subtype H1N1, as well as two different variants of bird flu subtype H5N1.

    The Company has previously announced excellent results in both animal studies and cell culture studies against widely different influenza subtypes and strains. If these results are confirmed in further animal and human studies, then FluCide would likely be considered the best ever drug effective against all influenzas. The Company is communicating its capabilities to various agencies involved in the current epidemic response.

    The current swine flu outbreak is significant in that the H1N1 virus causing it is novel (http://www.cidrap.umn....). The US Department of Homeland Security has declared a Swine Flu Emergency yesterday. The WHO has said that the outbreak is an emergency of international concern (http://www.upi.com/Hea...). The pig is known to be a transitional species for influenza viruses. That means re-assortment (i.e. mixing) of genes from bird flu, human flu, and swine flu viruses can take place in pigs. This can lead to more lethal, drug resistant novel strains to emerge from different existing ones.

    "Nanoviricides(™) have clear advantages over antibodies and vaccines as antiviral strategies," said Dr. Diwan, President of NanoViricides. Antibodies are relatively specific to a particular virus strain or subtype. It is well known that HIV and influenza viruses among many others, quickly escape antibodies. Vaccines depend upon the development of antibodies by the host, and thus, cannot protect efficiently against those viruses which are continually changing their character, such as the influenza virus. Influenza vaccines in particular have to be developed with the strain that is expected to infect in the next year’s cycle. It is well known that this is not a failure-proof strategy for epidemic-causing strains that are novel.

    About NanoViricides:

    NanoViricides, Inc. (nanoviricides.com) is a development stage company that is creating special purpose nanomaterials for viral therapy. The Company's novel nanoviricide™ class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. The Company is developing drugs against a number of viral diseases including H5N1 bird flu, seasonal Influenza, HIV, EKC, Hepatitis C, Rabies, Dengue fever, and Ebola virus, among others.

    This press release contains forward-looking statements .... more here

    Contact:

    NanoViricides, Inc.
    Amanda Schuon, 310-550-7200
    info@nanoviricides.com

    For commentary and my current outlook for NNVC, read "Kirk's Investment Newsletter"

    Disclaimer: I own NNVC in my personal and newsletter accounts with the last shares bought at 80¢. I have targets to take profits on these in the newsletter and my personal account should my price objective be reached. I will not announce this ahead of time here.


    NNVC PRICES
    DateClose
    $
    Volume
    24-Apr-090.80206,600
    23-Apr-090.6826,900
    22-Apr-090.7086,600
    21-Apr-090.73240,500
    20-Apr-090.6040,300
    17-Apr-090.6059,400
    16-Apr-090.6021,500


    Apr 27 10:42 AM | Link | 2 Comments
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