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  • Anavex May Actually Cure Alzheimer's [View article]
    The trials will consist of a prospective, multicenter, two-part study involving up to 300 mild-to-moderate AD patients.

    The first part is a scheduled Phase 1b/2a trial of approximately 40 patients who will receive either ANAVEX 2-73 or standard of care (donepezil) with ANAVEX 2-73. The study will explore dose and schedule as well as the efficacy of the combination. Patients in this study will have the option to rollover into a single open-label study in order to further accumulate safety, tolerability and efficacy data.

    The second part of the study is designed as a double-blind Phase 2 trial and will randomize AD patients to standard of care (donepezil) or standard of care (donepezil) with ANAVEX 2-73 with a primary outcome measure at 26 weeks efficacy based on standard cognitive measures. All patients from this second study will also have the option to rollover into the single open-label study in order to further accumulate safety, tolerability and efficacy data.

    - See more at: http://tinyurl.com/ppy...
    Jul 29, 2015. 02:01 PM | 1 Like Like |Link to Comment
  • Anavex May Actually Cure Alzheimer's [View article]
    the next Phase 2 trial following this one will have 300 patients, I read it in their documents
    Jul 29, 2015. 01:58 PM | Likes Like |Link to Comment
  • Anavex May Actually Cure Alzheimer's [View article]
    read the poster they released, it explains it all. Phase 2 will require 300 patients, not 32...
    Jul 29, 2015. 08:22 AM | 1 Like Like |Link to Comment
  • Anavex May Actually Cure Alzheimer's [View article]
    I believe there are 33mm warrants at .30 and another 33mm at .42 exerciseable

    That will take the share count to 150 plus million quickly, but would get about 20mm of cash via warrants as well
    Jul 27, 2015. 03:55 PM | 3 Likes Like |Link to Comment
  • Calithera Bio up 20% on CFO buy [View news story]
    he exercised options at 2.64. hardly a buy...
    Jul 18, 2015. 12:00 PM | Likes Like |Link to Comment
  • This Is Why Impac Mortgage Is Suddenly Getting Hammered [View article]
    The Pickup Family controls some 40% of the company equity/debt. They recently bought 500,000 worth of stock in the open market at 17.25-18.50... I think this was mostly a tight float trading situation.
    Jun 11, 2015. 08:16 AM | 1 Like Like |Link to Comment
  • Impac Mortgage Is A Story To Watch In 2015 [View article]
    We recommended the stock today at 17.25
    Jun 3, 2015. 09:36 PM | 2 Likes Like |Link to Comment
  • T2 Biosystems: Significant Upside Ahead With Hospital Contract Ramp-Up And Strong Pipeline [View article]
    we wrote a full report at 15 to our SRP Subscribers and we continue to be long the stock.
    Jun 3, 2015. 09:33 PM | 1 Like Like |Link to Comment
  • A Catalyst For WMI Holdings To Finally Begin Utilizing Their NOLs [View article]
    We come up with a fair value of about $2.83 per share as a shell. Basically this is trading at a bit of a discount, almost like a closed end fund below NAV.

    Loosely we assume 530 million fully diluted shares
    We take 6 Billion of NOL's and discount at 6% over 10 years use to get 3.3 Billion
    We take 28% of that for tax amount or about 900 million

    We add the cash of 600 million plus 900 million and come up with about 1.5 Billion

    Divided by 530mm fully diluted we are around $2.83 per share

    Its quick and dirty, but relatively accurate plus minus 5-8% or so on either side.

    SO you can buy the stock at 2.50 here on this pullback and have about a 10-13% discount to fair value before anything gets started.

    Just our 2...
    Apr 29, 2015. 12:31 PM | 2 Likes Like |Link to Comment
  • Concert Pharmaceuticals: The Deuterated Drug Platform, A Profitable Way To Reinvent The Wheel [View article]
    one of our favorites
    Apr 18, 2015. 10:45 AM | 3 Likes Like |Link to Comment
  • Celladon's Cardiovascular Fast Track MYDICAR Candidate Could Provide Upside [View article]
    As in full FDA approval, they could give conditional use approval with safety studies ongoing
    Apr 3, 2015. 05:34 PM | Likes Like |Link to Comment
  • Celladon's Cardiovascular Fast Track MYDICAR Candidate Could Provide Upside [View article]
    FDA approval, we dont mean phase2b data hitting... we mean FDA approval, that could be another 12-18 months etc...
    Apr 2, 2015. 09:43 PM | Likes Like |Link to Comment
  • Celladon: The Next Breakthrough In Cardiovascular Gene Therapy? [View article]
    NO, our plan all along was load up at 16-18, then sell at 21-23 if it got there 1/2 of the position before MYDICAR. Then ROTH Came out with a $70 target and all heck broke loose, we sold at 26-27 at our service in that March 12-13 window 1/2. We held 1/2 and that is our plan holding that 1/2 into MYDICAR data...
    Mar 31, 2015. 04:09 PM | 2 Likes Like |Link to Comment
  • Celladon: The Next Breakthrough In Cardiovascular Gene Therapy? [View article]
    yep...we wrote this up at 17 in January. Sold half at 26...holding rest
    Mar 31, 2015. 08:49 AM | 3 Likes Like |Link to Comment
  • Trevena's Q4 2014 Results Conference Call - What We Learned [View article]
    We continue to like this one long term, our report came out March 12th at 5.75... nice pullback this week, it got pretty overheated with retail chasers... slow and steady wins the race...
    Mar 28, 2015. 12:30 PM | Likes Like |Link to Comment
COMMENTS STATS
305 Comments
278 Likes