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Wednesday, Dec 19
2012, 7:25 PM
The FDA says that the blood thinner Pradaxa is not safe for use on patients with mechanical...
The FDA says that the blood thinner Pradaxa is not safe for use on patients with mechanical heart valves. A clinical trial in Europe was recently stopped because users were more likely to experience strokes, heart attacks, and blood clots forming on the mechanical heart valves than were users of the anticoagulant warfarin. There was also more bleeding after valve surgery in Pradaxa users than in warfarin users. Pradaxa's competitors include: Eliquis, from Bristol-Myers Squibb (BMY) and Pfizer (PFE), Xarelto from Johnson & Johnson (JNJ) and Coumadin, an older drug that's also from BMY.