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Chris DeMuth Jr. is the founder of Rangeley Capital LLC. Rangeley is an investment firm that focuses on event driven, value-oriented investment opportunities. Rangeley Capital and his value investing forum, Sifting the World (StW), search the world for misplaced bets. Rangeley exploits them for... More
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  • MS Patient Fights FDA Over Rejection Of Genzyme's Lemtrada 4 comments
    Jan 10, 2014 3:10 PM | about stocks: SNY

    You may be interested in this recent press from the Boston Business Journal,

    A 49-year-old mother from Waterford, Conn., has become an ally of Cambridge, Mass.-based drug giant Genzyme in its efforts to get U.S. regulators to change their minds about the first-ever once-a-year drug to treat multiple sclerosis.

    Melissa Burdick is a 49-year-old patient with multiple sclerosis who filed a citizen's petition in hopes of overturning the FDA's rejection of Lemtrada.

    According to its author, this is a

    "cool story on a Connecticut woman who may do more than a multi-billion dollar drug company can to change the FDA's mind on a potential $3.5B drug for multiple sclerosis."

    Stocks: SNY
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Comments (4)
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  • jaginger
    , contributor
    Comments (813) | Send Message
    Best wishes to you, Melissa. I do indeed hope that you are able to receive the best remedies available.
    10 Jan 2014, 03:25 PM Reply Like
  • Chris DeMuth Jr.
    , contributor
    Comments (11101) | Send Message
    Author’s reply » Treating MS with Campath (Lemtrada): -- this is worth listening to.
    10 Jan 2014, 06:11 PM Reply Like
  • John Wilson
    , contributor
    Comments (2024) | Send Message


    I sympathize with her, and while I hope she could get the treatment she wants, (and I don't know anything about Lemtrada), I would always try to look for a cause of the disease/condition.


    The view of Medical science does not look back to any causation of nutritional or mineral deficiency. It only looks forward to a patentable drug.


    While I have never looked into a possible cause of MS ever before, in less than 10 minutes I learned of possible causes of MS.


    The disease "... MS is caused by damage to the myelinsheath, the protective covering that surrounds nerve cells"


    "Multiple sclerosis has no cure." -Mayo


    Magnesium deficiency and mercury damage?


    The MS symptoms of myelin destruction are very similar to that caused by mercury poisoning. Magnesium deficiency can result in the nervous system's inability to protect itself from heavy metals like mercury. And a yearly regimen of vaccines may supply your system with mercury in the form of thimerasol.


    While the FDA may be dragging their feet at approving the use of Lemtrada, there is even less chance they will tell anyone about mineral/nutritional deficiencies. And there is no chance they will tell you about myelin damage from thimerasol in vaccines.


    Magnesium, zinc, iodine, sulfur - elements that cost almost nothing. And because they cost nothing, is the reason the medical establishment will never recognize the deficiency of them as a possible cause of MS.


    A doctor cures herself of MS


    My thoughts on the healthcare system:



    11 Jan 2014, 10:31 PM Reply Like
  • TimeOnTarget
    , contributor
    Comments (3638) | Send Message
    @John Wilson --


    While I understand your point, it is not that easy. There are a variety of diseases that have pathologies somewhat similar to MS, i.e., through impairing glial cell growth, health, and function: Alzheimer's and Parkinson's spring immediately to mind as two others.


    I think if you research you will find that there have been extensive epidemiological efforts at finding the causes of these diseases. Mercury is a substance that is well worth taking considerable pains to avoid. I sincerely doubt, however, that exposure to any of the simple heavy metal toxicants is a primary cause: They would have zoomed in on that long before now.


    Your apparent point about the need to look at the health of the body and proper nutrition is certainly valid: My father was prescribed two different medications for restless leg syndrome that were having substantial negative side effects. I became concerned, researched the medications, researched the condition, went back over a molecular neurobiology textbook, and purchased a high quality, multi-compound magnesium supplement and told him to take it three times a week and had him stop the medications. His restless leg stopped.


    On the other hand, I am fairly sure the causes of the aforementioned diseases affecting the glial cell system are not nearly so simple as either nutritional deficiencies or exposure to mercury. I have begun looking at both PD and AD. With regard to PD, there have been some interesting studies correlating it to pesticide and herbicide exposure. With regard to AD, I am personally starting to think that Bisphenol A may be the culprit but that is based on some very preliminary and indirect work that is still kind of skirting around the edges.


    While I agree that prevention and reducing exposure to compounds such as endocrine disrupting chemical, pesticides, herbicides etc. is very much needed, I certainly don't think it is any panacea nor do I think it obviates in any way the need to develop medications that will help combat these diseases. Maybe someday long in the future we will quit creating new health care problems that require expensive solutions, but now we are a long, long way from that.
    12 Jan 2014, 03:12 PM Reply Like
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