• Dr. Philippe Généreux to present new insights on the impact of calcified lesions during DES Summit including an ORBIT II case presentation by Dr. Jeffrey Chambers
• Dr. Gregg Stone and Dr. Gary Mintz to moderate the Challenges of Coronary Calcification session featuring a review of the ORBIT Studies by Dr. Jeffrey Chambers
• Dr. Juan Granada and Dr. Barry Katzen to moderate the Emerging Technologies for Peripheral Interventions session
• Dr. Jeffrey Chambers to present an ORBIT II clinical study coronary case

ST. PAUL, Minn.--(BUSINESS WIRE)-- Cardiovascular Systems, Inc. (CSII) (CSI) (NASDAQ: CSII), announced today that new findings regarding arterial calcification will be unveiled at the 2012 Transcatheter Cardiovascular Therapeutics (TCT) conference in Miami, Oct. 2226, 2012. Arterial calcification is a common, underdiagnosed condition and complicating factor for physicians treating peripheral arterial disease (PAD). It is estimated to be present in approximately 65 percent of the people treated annually for PAD.

CSI has also commenced its ORBIT II Investigational Device Exemption clinical trial to evaluate the safety and effectiveness of its orbital technology in treating coronary arteries. The coronary system is limited by federal law to investigational use and is currently not commercially available in the United States. Coronary arterial disease (CAD) is estimated to be present in approximately 38 percent of the people treated annually for CAD.

TCTs Drug Eluting Stent (DES) Summit: Appropriate Utilization of Current Generation Devices
What: Calcified Lesions: New Insights in Stable CAD and acute coronary syndrome (ACS) from Large-Scale Clinical Trials, presented by Dr. Philippe Généreux; and Decalcification with the Orbital Atherectomy System: Case Presentation (with discussion), presented by Dr. Jeffrey Chambers.

When: Monday, Oct. 22, 12:37 12:57 p.m.

Where: Miami Beach Convention Center, Hall A

TCT Sponsored Evening Sessions
Two evening sessions will explore the historical challenge of coronary calcification and emerging technologies for peripheral interventions.

Session #1
What: The Challenge of Coronary Calcification: From Yesterday to Tomorrow, moderated by Dr. Gregg Stone and Dr. Gary Mintz

When: Tuesday, Oct. 23, 6:30 8:45 p.m.

Where: Ritz Carlton South Beach Hotel, Salons 1-2

Session #2
What: Emerging Technologies for Peripheral Interventions: Device Selection, Technical Approach and Clinical Outcomes, presented by Dr. Juan Granada and Dr. Barry Katzen

When: Thursday, Oct. 25, 6:30 8:45 p.m.

Where: Loews Miami Beach Hotel, Americana Ballroom, Salon 4

ORBIT II Clinical Study Coronary Case
What: Dr. Jeffrey Chambers will conduct a live presentation of his ORBIT II case as part of the Coronary Interventions taped cases session. (See ORBIT II description below)

When: Oct. 25, 4:30 5:00 p.m.

Where: Miami Beach Convention Center, Presentation Theater 1

CSI Booth at TCT: Oct. 2325
Visit CSI at booth #926, noon 5 p.m., Tuesday, Oct. 23, and 9 a.m. 5 p.m. Wednesday, Oct. 24 and Thursday, Oct. 25.

About Peripheral Arterial Disease

PAD is a life-threatening condition where a fatty material called plaque builds up on the inside walls of the blood vessels that carry blood from the heart to legs and arms. The plaque buildup causes the arteries to harden and narrow (atherosclerosis), reducing blood flow to the legs. The risk of PAD increases if a person has one or several of the following: high blood pressure, abnormal cholesterol levels, diabetes, or personal history of heart disease, heart attack or stroke. PAD affects an estimated 8-12 million people in the United States. The disease prevalence increases with age and 12-20 percent of Americans age 65 and older suffer from PAD symptoms. As the U.S. population ages, the prevalence range could reach 16 million in those age 65 and older and 19 million overall by 2050.

About Cardiovascular Systems, Inc.

Cardiovascular Systems, Inc., based in St. Paul, Minn., is a medical device company focused on developing and commercializing innovative solutions for treating vascular and coronary disease. The companys Orbital Atherectomy Systems treat calcified and fibrotic plaque in arterial vessels throughout the leg in a few minutes of treatment time, and addresses many of the limitations associated with existing surgical, catheter and pharmacological treatment alternatives. The U.S. FDA granted 510(k) clearance for the use of the Diamondback Orbital Atherectomy System in August 2007. To date, nearly 100,000 of CSIs devices have been sold to leading institutions across the United States. CSI has also commenced its ORBIT II Investigational Device Exemption clinical trial to evaluate the safety and effectiveness of its orbital technology in treating coronary arteries. The coronary system is limited by federal law to investigational use and is currently not commercially available in the United States.

For more information, visit the companys website at www.csi360.com.

Cardiovascular Systems, Inc.
Investor Relations, 651-259-2800
investorrelations@csi360.com
or
Sarah Wozniak, 651-259-1636
swozniak@csi360.com
or
Padilla Speer Beardsley Inc.
Matt Sullivan, 612-455-1709
msullivan@padillaspeer.com
or
Dave Folkens, 612-455-1741
dfolkens@padillaspeer.com

Source: Cardiovascular Systems, Inc.

Copyright Business Wire 2012