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Sucampo Pharmaceuticals slips despite releasing positive top line data

  • Sucampo Pharmaceuticals (SCMP -3.3%) slips today, despite announcing earlier that it had achieved positive top-line results from two recently completed Phase 1a clinical trials of both cobiprostone and SPI-3608.
  • The studies tested the tolerability and pharmacokinetic profiles versus placebo of the two compounds, both of which were demonstrated to be generally well-tolerated in the tested populations.
  • SPI-3608 is being investigated for the treatment of mild to moderate lumbar spinal stenosis and may be investigated for additional indications in the future.
  • The next phase of development for SPI-3608 is expected to begin in the first quarter of 2014.
  • Data on cobiprostone showed that it induces mucosal barrier repair and prevents mucosal barrier damage, and the fact that it was well-tolerated in this study, the company says, is extremely encouraging.
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