Isis heart drug helps cut blood fat in trial


Isis' (ISIS) ISIS-APOCIIIRx reduced levels of triglycerides in blood by up to 75% and of apolipoprotein C-III by 79% in a Phase II study of 28 patients.

Triglycerides are a type of fat that raises the risk of heart disease, while apolipoprotein C-III prevents triglycerides from being cleared.

Patients also enjoyed increases of up to 57% in high-density lipoprotein (HDL), or "good," cholesterol.

ISIS-APOCIIIRx is based on Isis' antisense technology, which inhibits cells from producing proteins that cause diseases. (PR)

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Comments (5)
  • brown25
    , contributor
    Comments (63) | Send Message
     
    Wait, this is "triple counting". It is only allowed to have One positive effect!
    2 Sep 2013, 09:38 AM Reply Like
  • BlueSeas
    , contributor
    Comments (219) | Send Message
     
    Sounds like their confusing "Causation" and "Correlation". Sort of like when my cars gas gauge points to E then it stops so I'll fix the gauge so it only points to 1/2. There is plenty of evidence that cholesterol is not the cause but there is big money in saying it is.
    2 Sep 2013, 09:52 AM Reply Like
  • Yokyok
    , contributor
    Comments (327) | Send Message
     
    and of course we won't know for years what new problems the drug itself may cause
    2 Sep 2013, 02:07 PM Reply Like
  • brown25
    , contributor
    Comments (63) | Send Message
     
    That's true, I am just now feeling the side effects of drinking milk as a kid!
    2 Sep 2013, 06:47 PM Reply Like
  • brown25
    , contributor
    Comments (63) | Send Message
     
    So, How many McDonald franchises do you own?
    2 Sep 2013, 07:04 PM Reply Like
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