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Isis announces Phase 2 antisense data in FCS

Isis Pharmaceuticals (ISIS) outlines data from a Phase 2 trial of the antisense drug ISIS-APOCIIIRx in familial chylomicronemia syndrome.

All three patients saw "substantial reductions" (average was 69%) in triglyceride levels.

The disease only affects 3-5K patients worldwide, so the trial was quite small, but the data "are ... compelling and demonstrate the potential of ISIS-APOCIIIRx to produce dramatic triglyceride lowering in patients with FCS," Dr. Daniel Gaudet notes.

The company says "the significant unmet medical need [associated with FCS] should enable [ISIS to] rapidly move forward." (PR)

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Comments (2)
  • arthurs1
    , contributor
    Comments (376) | Send Message
    The ISIS train keps a rolling all night long.....even on weekends.
    21 Sep 2013, 04:40 PM Reply Like
  • brown25
    , contributor
    Comments (63) | Send Message
    I would like to take this opportunity to thank the "Tedster", Barons, and Con-Fusuion research to allow me to purchase more ISIS on the cheap last month!!!
    21 Sep 2013, 05:18 PM Reply Like
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