CEO Antony Jenkins said the bank has notified around half of the affected workers in Britain.
The bank employed 139,600 staff at the end of last year.
Barclays announced the job cuts as it revealed in its FY report that its bonus pool rose 10% to £2.38B.
The firm said its 2013 earnings were hurt by legal costs and restructuring, including its withdrawal from some businesses.
Shares are -1.25% in London.