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A ray of hope for ficlatuzumab

Apr. 10, 2014 7:50 AM ETAVEO Pharmaceuticals, Inc. (AVEO) StockAVEOBy: Douglas W. House, SA News Editor
  • AVEO Pharmaceuticals (NASDAQ:AVEO) and Biodesix cross license their IP regarding AVEO's hepatocyte growth factor inhibitory antibody and Biodesix's companion diagnostic test for non-small cell lung cancer VeriStrat.
  • Ficlatuzumab failed to demonstrate efficacy in its Phase 2 clinical trial but an exploratory analysis using VeriStrat identified a sub-group of patients who experienced PFS and OS.
  • AVEO intends to conduct a new clinical trial (NSCLC POC Trial) on patients selected with the VeriStrat test. Biodesix will fund the trial up to a maximum of $15M. Costs above the maximum will be borne equally.
  • If the product is approved for commercial sale, the partners will share all profits and losses on a 50/50 basis.

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