Encouraging data from NewLink immunotherapeutic study

Data from a 25-patient Phase 2 clinical trial evaluating NewLink Genetics' (NLNK) dorgenmeltucel-L HyperAcute immunotherapy in combination with pegylated interferon-alpha 2b for advanced metastatic, progressive, refractory or recurrent melanoma shows that the combo is capable of inducing complete and durable clinical responses with tumor regression and immune activation.

Of the sixteen patients with Stage IV disease, two had a complete response as defined by RECIST criteria, one had stable disease and four had no evidence of disease (NED) after resection. Of the nine patients with stage II/III disease, three remained NED and one stage IIC patient had slow progressive disease (PD) with a single site resected is currently NED.

Twelve of the 25 subjects are still alive. All evaluable patients (21/21) seroconverted.

The complete response rate was 12.5% in patients with metastatic disease and the responses were durable.

Shares are up 10% premarket on fairly good volume.

From other sites
Comments (0)
Be the first to comment
DJIA (DIA) S&P 500 (SPY)
ETF Screener: Search and filter by asset class, strategy, theme, performance, yield, and much more
ETF Performance: View ETF performance across key asset classes and investing themes
ETF Investing Guide: Learn how to build and manage a well-diversified, low cost ETF portfolio
ETF Selector: An explanation of how to select and use ETFs