The USPTO issues patent no. 8,618,277 to Alnylam (ALNY +1.3%) in its McSwiggen patent estate, which broadly describes chemical modifications of RNAi therapeutics needed to achieve drug-like properties in siRNA. The 277 patent includes important claims related to the development of RNAi therapeutics for the treatment of hepatitis B infection. It is exclusive to the company.
The McSwiggen patent estate includes 23 granted patents around the world and is a core component of Alnylam's IP portfolio for the advancement of RNAi therapeutics. It obtained the estate via its acquisition of Sirna Therapeutics from Merck (MRK -1%).