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CTI completes clinical trial enrollment that sets up a milestone payment

  • CTI BioPharma (CTIC) completes enrollment in the PERSIST-1 Phase 3 clinical trial of pacritinib, an oral JAK2/FLT3 inhibitor being evaluated as a treatment for myelofibrosis. Under the terms of the development and commercialization agreement with Baxter International (BAX), CTI expects to receive a $20M milestone payment when the last patient in the trial begins dosing. The payment should occur this quarter.
  • There are approximately 320 patients enrolled in PERSIST-1. It is a randomized, open-label multicenter study comparing the safety and efficacy of pacritinib with best available therapy, other that JAK inhibitors, in patients with primary myelofibrosis without exclusion for low platelet counts. The primary endpoint is the percentage of patients achieving at least a 35% reduction in spleen volume measured by MRI or CT at 24 weeks of treatment.
Comments (1)
  • bonifax 1
    , contributor
    Comments (39) | Send Message
     
    In previous comments I indicated, more 'times, the underestimation of the title.
    This is' another milestone for the $ 362 million that Baxter will donate 'to the Company'. The Current ipeline worth at least $ 8.50
    1 Jul, 09:08 AM Reply Like
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