- Patient enrollment in the 260-patient Phase 2 clinical trial evaluating Synergy Pharmaceuticals' (SGYP -5.7%) uroguanylin analog SP-333 as a treatment for opioid-induced constipation (OIC) is complete. The randomized double-blind study will compare the safety and efficacy of SP-333 versus placebo in patients taking opioid analgesics for chronic non-cancer pain for at least three months. The primary endpoint is the mean change from baseline in the number of spontaneous bowel movements during Week 4 of the Treatment Period.
- Synergy intends to release top-line data from the trial in Q4.
- Related tickers: (NKTR -5.2%) (AZN -2.1%) (CBST -0.8%) (SLXP -1.6%) (PGNX)
Patient enrollment for Synergy OIC drug trial complete
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