- Halozyme Therapeutics (NASDAQ:HALO) and Janssen Biotech (JNJ) enter into a worldwide Collaboration and License Agreement to develop and commercialize products based on Halozyme's Enhanze technology, which is based on HALO's proprietary recombinant human hyaluronidase enzyme (rHuPH20) that temporarily modifies hyaluronan, a component of the extracellular matrix, to aid in the dispersion and absorption of injected therapeutic drugs.
- Under the terms of the contract, Halozyme grants Janssen a global license to develop and commercialize products for up to five targets combining rHuPH20 with Janssen's proprietary compounds. Halozyme will receive an upfront payment of $15M and up to $566M in development, regulatory and sales milestones plus royalties on commercial sales.