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Bristol-Myers' Daklinza, in combo with other agents, shows cure rates as high as 100% in HCV-3 patients in late-stage study

Nov. 16, 2015 11:21 AM ETBristol-Myers Squibb Company (BMY) StockBy: Douglas W. House, SA News Editor5 Comments
  • Results from a Phase 3 clinical trial, ALLY-3+, evaluating the combination of Bristol-Myers Squibb's (NYSE:BMY +0.3%) Daklinza (daclatasvir), Gilead's (GILD -0.5%) Sovaldi (sofosbuvir) and ribavirin (RBV) in HCV-3 patients with advanced fibrosis or cirrhosis show cure rates as high as 100% after 12 - 16 weeks. The data will be presented today at The Liver Meeting in San Francisco.
  • 100% of the patients in the advanced fibrosis cohort achieved SVR12 in both the 12- and 16-week arms. In the cirrhosis cohort, the cure rates in the 12- and 16-week arms were 83% and 89%, respectively.
  • Daklinza, approved by the FDA in July, is an NS5A inhibitor indicated for the treatment of HCV-3-positive adults (in combination with Sovaldi).

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