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Allergan Inc. (AGN)

  • Fri, Feb. 13, 9:45 AM
    • Actavis (ACT -0.2%) sells its Aptalis subsidiary's Aptalis Pharmaceutical Technologies, known as Pharmatech, to private equity firm TPG for an undisclosed sum. The transaction is expected to close mid-year.
    • Pharmatech is an oncology-focused contract research organization (CRO) and clinical trial site manager (SMO). Current President of Aptalis Pharmaceutical Technologies John Fraher will be CEO of the new standalone firm.
    • Actavis COO Robert Stewart says, "Our decision to divest the Pharmatech business is consistent with our strategic commitment t build leadership positions in our core areas of strength. It will enable our industry-leading Global Operations team to sharpen their focus on supporting our existing global supply chain and on preparing for the expansion of our manufacturing network with the addition of the Allergan facilities following the close of the acquisition later this year."
    | Fri, Feb. 13, 9:45 AM | Comment!
  • Mon, Feb. 9, 5:49 PM
    • Australia's Mayne Pharma (OTCPK:MAYNF) is buying the U.S. rights to the Doryx acne treatment from Actavis (NYSE:ACT) for $50M. The deal is expected to close by month's end.
    • Actavis exec William Meury: "By agreeing to return the product to Mayne now, we receive value for the asset and, following a brief transition period, will enable our sales and marketing teams to focus their time and attention on supporting the expanded, industry-leading Dermatology portfolio that will be part of our combined company following the acquisition of Allergan later this year."
    • Actavis is just a few days removed from announcing a deal to sell its North American respiratory business to AstraZeneca.
    | Mon, Feb. 9, 5:49 PM | Comment!
  • Fri, Feb. 6, 9:20 AM
    • According to some observers, Pfizer's (NYSE:PFE) $17B takeout of Hospira (NYSE:HSP) is only a prelude to a bigger deal(s) considering that it was prepared to spend $120B for AstraZeneca (NYSE:AZN).
    • According to Gabelli analyst Kevin Kedra, Actavis Plc (NYSE:ACT) is an attractive target, especially since nabbing Allergan (NYSE:AGN) and its fast-growing drug portfolio. A Pfizer takeover would be big enough to overcome the U.S. Treasury's stricter rules on inversions and lower its tax bill.
    • John Boris of SunTrust Banks says GlaxoSmithKline (NYSE:GSK), AbbVie (NYSE:ABBV), Bristol-Myers Squibb (NYSE:BMY) and Mylan (NASDAQ:MYL) may be on the radar as well.
    • Pfizer had $33B in cash at the end of September which it will use a portion of plus debt to pay for Hospira.
    | Fri, Feb. 6, 9:20 AM | 6 Comments
  • Fri, Feb. 6, 8:16 AM
    • In an effort to sharpen its focus on its core therapeutic areas, Actavis (NYSE:ACT) divests its branded respiratory assets for the treatment of chronic obstructive pulmonary disease (COPD) in the U.S. and Canada to AstraZeneca (NYSE:AZN). Under the terms of the agreement, AZN will pay ACT $600M plus low single-digit royalties above a certain revenue threshold.
    • AstraZeneca will own the development and commercial rights to Tudorza Pressiar (aclidinium bromide inhalation powder) and Daliresp (roflumilast). Sales for both products last year were $230M. AZN will also secure the development rights in the U.S. and Canada for LAS40464, which it sells in the E.U. under the brand name Duaklir Genuair.
    • Actavis will receive an additional $100M from AstraZeneca on the basis of certain amendments to the firms' ongoing collaboration agreements.
    • The transaction should close this quarter.
    | Fri, Feb. 6, 8:16 AM | Comment!
  • Thu, Feb. 5, 4:32 AM
    • AstraZeneca (NYSE:AZN) reported a fourth-quarter loss this morning, but stressed that it was on track to return to growth by 2017.
    • The company's fourth-quarter net loss came in at $321M, down 38% from $524M a year earlier, while sales for the last three months of the year fell 2% to $6.68B.
    • Actavis (NYSE:ACT) also confirmed that AstraZeneca would buy its branded respiratory business in the U.S. and Canada for an initial $600M.
    • ACT -1.7% premarket
    | Thu, Feb. 5, 4:32 AM | Comment!
  • Wed, Feb. 4, 5:02 PM
    • Allergan (NYSE:AGN) Q4 results ($M): Revenues: 1,910.5 (+13.4%); Operating Income: 626.7 (+37.8%); Net Income: 539.1 (+72.6%); EPS: 1.76 (+69.2%); Quick Assets: 4,966.4 (+36.1%).
    • Eye Care Pharmaceuticals: 881.7 (+12.7%); Botox/Neutomodulators: 589.3 (+12.1%); Skin Care & Other: 135.7 (+11.3%); Breast Aesthetics: 99.5 (+11.0%); Facial Aesthetics: 174.2 (+27.0%); Total Medical Devices: 282.3 (+22.8%).
    • Key Product Sales: Alphagan P/Alphagan/Combigan: 138.5 (+10.9%); Lumigan Franchise: 177.3 (+2.7%); Total Glaucoma: 317.7 (6.0%); Restasis: 309.4 (+11.5%); Latisse: 27.4 (+17.1%).
    • No guidance provided.
    | Wed, Feb. 4, 5:02 PM | 3 Comments
  • Wed, Feb. 4, 4:54 PM
    • Allergan (NYSE:AGN) declares $0.05/share quarterly dividend, in line with previous.
    • Forward yield 0.09%
    • Payable March 20; for shareholders of record Feb. 9; ex-div Feb. 5.
    | Wed, Feb. 4, 4:54 PM | Comment!
  • Wed, Feb. 4, 4:42 PM
    • Allergan (NYSE:AGN): Q4 EPS of $2.17 beats by $0.34.
    • Revenue of $1.91B (+13.7% Y/Y) beats by $10M.
    • Press Release
    | Wed, Feb. 4, 4:42 PM | Comment!
  • Sat, Jan. 31, 12:35 PM
    • The FDA approves Zogenix's (NASDAQ:ZGNX) Zohydro ER (hydrocodone bitartrate) Extended-Release Capsules, CII, with BeadTek, a formulation technology that provides abuse-deterrent features without changing the release properties of hydrocodone.
    • BeadTek incorporates pharmaceutical excipients that immediately form a viscous gel when crushed and dissolved in liquids or solvents.
    • The company intends to transition all Zohydro strengths to the BeadTek version in Q2. In H2, it expects to submit the results from its ongoing Human Abuse Liability Studies, which will further characterized the abuse-deterrent properties of the BeadTek formulation, to the FDA.
    | Sat, Jan. 31, 12:35 PM | 7 Comments
  • Mon, Jan. 26, 10:20 AM
    • Actavis (ACT +1.1%) acquires Middlesex-based Auden Mckenzie for ₤306M, making Actavis the largest supplier of generic medicines in the U.K. The transaction will be accretive to earnings this year.
    • Auden markets a line of 175 products with an additional 40 in development.
    | Mon, Jan. 26, 10:20 AM | 1 Comment
  • Thu, Jan. 15, 7:22 AM
    • In an effort to increase its focus on developing new drugs, privately-held Boehringer Ingelheim says that it is considering the sale of Roxane Labs, its U.S.-based generics unit. The company believes it makes more sense for a generics specialist to own the 1,300-employee business.
    • The generics industry is fiercely competitive as the number of blockbuster drugs coming off patent has declined from its peak in 2012. The top players are (NYSE:TEVA), Sandoz (NYSE:NVS) and Actavis (NYSE:ACT).
    • According to Bloomberg, Roxane could fetch as much as $2.4B. Morgan Stanley is advising.
    | Thu, Jan. 15, 7:22 AM | Comment!
  • Mon, Jan. 12, 9:34 AM
    • The U.S. Federal Trade Commission grants early termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976 in regard to Actavis' (ACT +1.2%) pending takeout of Allergan (AGN +1.9%). This satisfies one of the conditions for the transaction.
    • The record date for determining eligible shareholders who will be entitled to vote on the deal is January 22.
    | Mon, Jan. 12, 9:34 AM | Comment!
  • Mon, Jan. 12, 8:56 AM
    • Actavis (NYSE:ACT) will report Q4 and full-year results on February 18.
    • Consensus revenue views for Q4 and 2014 are $3.8B and $12.65B, respectively.
    | Mon, Jan. 12, 8:56 AM | Comment!
  • Thu, Jan. 8, 4:19 PM
    • Adamas Pharmaceuticals (NASDAQ:ADMS) receives a $30M milestone payment from Actavis (NYSE:ACT) subsidiary Forest Laboratories for the FDA clearance of Namzaric (memantine hydrochloride/donepezil hydrochloride) for the treatment of moderate-to-severe dementia of the Alzheimer's type in patients stabilized on memantine hydrochloride and donepezil hydrochloride.
    • Forest submitted the NDA in February 2014.
    • Previously: FDA clears Adamas Alzheimer's drug (Dec. 24, 2014)
    | Thu, Jan. 8, 4:19 PM | Comment!
  • Thu, Jan. 1, 2:19 AM
    | Thu, Jan. 1, 2:19 AM | 17 Comments
  • Dec. 24, 2014, 8:52 AM
    • The FDA approves the New Drug Application (NDA) for Namzaric, a fixed dose combination of memantine HCl extended release and donepezil hydrochloride, for the treatment of moderate-to-severe dementia of the Alzheimer's type.
    • Memantine is an NMDA receptor agonist which blocks the activity of the neurotransmitter glutamate. At normal levels, glutamate aids memory and learning but it the levels are excessive, it overstimulates and eventually kills nerve cells via excitotoxicity.
    • Donepezil is a reversible acetylcholinesterase inhibitor. It inhibits the hydrolysis of acetylcholine which is a process associated with cognitive impairment.
    • Namzaric was co-developed by Adamas Pharmaceutics (NASDAQ:ADMS) and Forest Laboratories (NYSE:ACT) under the terms of an agreement signed in November 2012.
    • Adamas is due a $30M milestone payment from Forest for the approval.
    • ADMS is up 19% premarket on moderate volume.
    | Dec. 24, 2014, 8:52 AM | Comment!
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Company Description
Allergan PLC is a specialty pharmaceutical company. The Company is engaged in developing, manufacturing and distributing generic, brand and biosimilar products.