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BioCryst Pharmaceuticals, Inc.NASDAQ
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  • Tue, Nov. 29, 3:12 AM
    • Texas has reported its first home-grown case of Zika virus - making it the second U.S. state with mosquitoes spreading the disease.
    • It's a long-feared development but not a surprising one. Like Florida, South Texas is home to the Aedes aegypti mosquitoes that spread Zika and also hosts many travelers to and from countries where the virus has been spreading.
    • Related tickers: SNY, ABT, INO, AEMD, XON, CEMI, BCRX, TMO, OSUR, OTCQB:GOVX
    | Tue, Nov. 29, 3:12 AM | 6 Comments
  • Mon, Nov. 7, 6:53 AM
    • BioCryst Pharmaceuticals (NASDAQ:BCRX): Q3 EPS of -$0.16 beats by $0.08.
    • Revenue of $7.76M (-29.4% Y/Y) beats by $1.82M.
    • Press Release
    | Mon, Nov. 7, 6:53 AM
  • Sun, Nov. 6, 5:30 PM
  • Fri, Oct. 14, 2:28 AM
    • Florida officials have announced a new area of Zika transmission in Miami, which has already infected five individuals, and called on the federal government for funding to help fight the virus.
    • It's the third established outbreak in the city, a hot zone for Zika because it has both the Aedes mosquitoes that transmit the disease, and an influx of travelers from other areas where the virus is spreading.
    • Related tickers: SNY, ABT, INO, AEMD, XON, CEMI, BCRX, TMO, OSUR, OTCQB:GOVX
    | Fri, Oct. 14, 2:28 AM | 17 Comments
  • Wed, Oct. 5, 5:35 AM
    • Florida officials are warning that Hurricane Matthew could complicate efforts to control Zika by interrupting mosquito-spraying efforts and boosting numbers of the biting bugs that spread the virus.
    • The warnings come as authorities reported six new suspected non-travel-related Zika cases in Miami Beach and Miami-Dade County, bringing the number of cases where local mosquitoes are believed to have caused infections to 139.
    • Related tickers: SNY, ABT, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX, OSUR
    | Wed, Oct. 5, 5:35 AM | 22 Comments
  • Tue, Sep. 13, 2:49 AM
    • After meeting with the top four congressional leaders on Monday, President Obama said he was encouraged that lawmakers would be able to reach an agreement on funding to fight the Zika virus.
    • In February, Obama had asked Congress to approve $1.9B in emergency funds to battle Zika with diagnostic tools and vaccines, but disagreements over side issues related to abortion led to divisions about full funding.
    • Related tickers: SNY, ABT, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX, OSUR
    | Tue, Sep. 13, 2:49 AM | 19 Comments
  • Fri, Sep. 9, 5:34 AM
    • Pre-dawn aerial spraying for Zika-carrying mosquitoes has begun in Miami Beach, but it's bugging out some locals due to health concerns surrounding insecticide Naled.
    • Originally scheduled for Thursday, the spraying was delayed for a day after angry residents protested.
    • So far there have been 56 locally transmitted and 596 travel-related Zika cases in Florida. According to the CDC, there are 2,977 cases of the virus in the continental U.S.
    • Related tickers: SNY, ABT, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX, OSUR
    | Fri, Sep. 9, 5:34 AM | 40 Comments
  • Sun, Aug. 28, 12:52 PM
    • Singapore authorities have identified 41 Zika cases that were transmitted locally, and warned that they expect to find more.
    • The cases appear to be the largest single beachhead the virus has made in Asia in the current epidemic, which has also been detected in countries like Bangladesh, Malaysia and the Philippines.
    • On Thursday, China added the U.S. to a list of Zika-infected countries, worrying U.S. exporters, who fear they will be required to fumigate containers destined for Chinese ports.
    • Related tickers: SNY, ABT, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX, OSUR
    | Sun, Aug. 28, 12:52 PM | 18 Comments
  • Sun, Aug. 21, 8:56 AM
    • Federal health officials are warning pregnant women and their partners not to travel to Miami Beach after Florida confirmed that the mosquito-borne Zika virus was active in the popular tourist destination.
    • The CDC also suggested that pregnant women who are especially worried about Zika exposure might consider avoiding all of Miami-Dade County.
    • Other fears? In addition to causing the birth defect microcephaly, a new study from Rockefeller University and La Jolla Institute for Allergy and Immunology suggests the virus may cause brain damage in adults as well.
    • Related tickers: SNY, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX
    | Sun, Aug. 21, 8:56 AM | 50 Comments
  • Sun, Aug. 14, 1:03 PM
    • Three new non-travel cases of the Zika virus have been found in Florida, including another person who doesn't live in the one-square-mile area believed to be the hub of local transmission, bringing the number of cases confirmed there so far to 28.
    • The U.S. Centers for Disease Control and Prevention issued a warning two weeks ago for pregnant women to avoid this area of Miami. Zika has been shown to cause birth defects, including microcephaly, which causes severe developmental problems.
    • Related tickers: SNY, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX
    | Sun, Aug. 14, 1:03 PM | 25 Comments
  • Fri, Aug. 12, 4:38 AM
    • The Obama administration will transfer a total of $81M within the Department of Health and Human Services to work on Zika vaccines amid an increase in cases in the United States.
    • The money is intended to keep research going despite the lack of funding from U.S. lawmakers, who left for summer recess before allocating funds to halt the spread of the virus.
    • Related tickers: SNY, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX
    | Fri, Aug. 12, 4:38 AM | 23 Comments
  • Thu, Aug. 11, 11:04 AM
    • BioCryst Pharmaceuticals (BCRX -1%) announces that the first subject has been dosed in its two-part Phase 2 clinical trial, APeX-1, assessing next-generation killikrein inhibitor BCX7353 for the treatment of hereditary angioedema (HAE).
    • APeX-1 is a randomized, double-blind, placebo-controlled dose-ranging study that will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of BCX7353 in ~50 HAE patients. Part 1 will randomize subjects 1:1 to receive either a once-daily oral dose of 350 mg of BCX7353 or placebo for four weeks. An interim analysis will be performed after the first 24 patients have completed 28 days of treatment. If a significant treatment effect is observed, Part 2 will be initiated. If the data aren't robust enough, 12 more patients will be recruited in Part 1. The sample size is flexible by design in order to cover a range of response options that will achieve statistical significance based on a reduction in HAE attack rate of at least 70% in the BCX7353 cohort, a placebo response rate of ~30% and a standard deviation of ~0.45 attacks/week.
    • Part 2 will characterize the dose responses in 14 additional patients who will be randomized to receive either 250 mg or 125 mg of BCX7353 once daily or placebo.
    • HAE is a rare inherited condition characterized by excessive swelling in the extremities, face, genitalia and airway, which can be life-threatening. A peptide called bradykinin is the mediator of acute swelling attacks in HAE sufferers. BCX7353 inhibits plasma kallikrein, an enzyme that plays a key role in bradykinin production.
    • The company's first-generation killikrein inhibitor, avoralstat, failed to beat placebo in a Phase 2/3 HAE study.
    • Read now BioCryst Where To Go From Here?
    | Thu, Aug. 11, 11:04 AM | 1 Comment
  • Sun, Aug. 7, 12:40 PM
    • As fears mount about the impacts of Zika, Canaccord's Tony Dwyer is warning that the health crisis (compounded with Italian bank issues, a more hawkish Fed and energy price weakness) could morph into the Ebola scare that enveloped the market two years ago.
    • The S&P 500 slipped 1.7% off its peak once the first U.S. Ebola case was reported in September 2014, and by the time the third American case was diagnosed, the market was already down 7%.
    • "Obviously, no two situations are exactly alike, but this is pretty close," concluded Dwyer. "I'm not looking for anything like a 10% decline... but this could be the catalyst we've been looking for."
    • Related tickers: SNY, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX
    | Sun, Aug. 7, 12:40 PM | 58 Comments
  • Thu, Aug. 4, 10:55 AM
    • BioCryst Pharmaceuticals (BCRX +1.7%) Q2 results: Revenues: $4.8M (-81.4%); R&D Expense: $14.2M (-13.9%); SG&A: $2.7M (-22.9%); Operating Loss: ($12.1M); Net Loss: ($16.3M); Loss Per Share: ($0.22); Quick Assets: $59.9M (-39.6%).
    • 2016 Guidance: Net operating cash use: $55M - 75M; Operating Expenses: $78M - 98M.
    | Thu, Aug. 4, 10:55 AM
  • Thu, Aug. 4, 6:59 AM
    • BioCryst Pharmaceuticals (NASDAQ:BCRX): Q2 EPS of -$0.22 beats by $0.04.
    • Revenue of $4.79M (-81.5% Y/Y) beats by $0.87M.
    • Press Release
    | Thu, Aug. 4, 6:59 AM
  • Thu, Aug. 4, 5:01 AM
    • U.S. government researchers have begun their first clinical trial of a Zika vaccine while the Obama administration told lawmakers funds to fight the virus would run out in the coming weeks due to congressional inaction.
    • The number of locally spread Zika cases has jumped to 15 in Florida and the amount of U.S. states affected has reached 45. As of July 27, 1,658 travel associated cases of Zika were reported across the continental U.S. and Hawaii.
    • Related tickers: SNY, INO, AEMD, XON, CEMI, BCRX, TMO, OTCQB:GOVX
    | Thu, Aug. 4, 5:01 AM | 21 Comments