Celgene Corporation
 (CELG)

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  • Thu, Jan. 28, 7:32 AM
    • Celgene (NASDAQ:CELG): Q4 EPS of $1.18 misses by $0.04.
    • Revenue of $2.56B (+22.5% Y/Y) beats by $20M.
    • Shares +1.62% PM.
    • Press Release
    | Thu, Jan. 28, 7:32 AM
  • Wed, Jan. 27, 3:30 PM
    • As if biotech investors need reminding, biotechs (and healthcare stocks) are getting some rude treatment today, the market's foul mood notwithstanding. The Nasdaq Composite Index is down 2.5%,but the SPDR S&P Biotech ETF (XBI -4.7%) almost twice as much. The iShares Nasdaq Biotechnology ETF (IBB -3.5%) is faring a bit better, but still down more than the broad market.
    • Only Biogen and Abbott have bucked the trend.
    • Sample of tickers: (AMGN -2.5%)(BIIB +5.7%)(CELG -3.9%)(GILD -3.3%)(ALXN -1.2%)(ABT +0.3%)(BMY -1.8%)(MRK -3%)(VRX -4%)(PFE -0.9%)
    • ETFs: BIB, BIS, CNCR
    | Wed, Jan. 27, 3:30 PM | 60 Comments
  • Wed, Jan. 20, 1:47 PM
    • It appears that biotech investors have had enough of the sidelines. Many tickers are showing bullish reversals.
    • Representative tickers: (RLYP +15.3%)(CELG +2.6%)(AMGN +0.2%)(BIIB -1.6%)(ALXN -0.6%)(VRTX +0.2%)(IBB +0.8%)(XBI +2.1%)
    | Wed, Jan. 20, 1:47 PM | 20 Comments
  • Wed, Jan. 20, 11:36 AM
    • To point out the obvious, the biotech sector has been unable to fight off the widespread selling. The iShares Nasdaq Biotech Index Fund (IBB -1.8%) is down again, albeit on modestly higher volume. It's down over 21% since late December.
    • Representative tickers: (GILD -1.7%)(CELG +0.7%)(BIIB -2.7%)(AMGN -0.6%)(ALXN -2.8%)
    | Wed, Jan. 20, 11:36 AM | 17 Comments
  • Mon, Jan. 11, 12:24 PM
    • Celgene (CELG -5.9%) slumps on double normal volume after it released its 2016 guidance of non-GAAP EPS of $5.50 - 5.70 (+19%) on revenues of $10.5B - 11.0B (+17%), both below the growth rates for 2015. GAAP EPS is expected to be $4.26 - 4.64. REVLIMID forecast: $6.6B - 6.7B.
    • Preliminary 2015 results: total revenues: $9.16B (+21%); non-GAAP EPS: ~$4.71 (+27%); GAAP EPS: $1.89 - 1.99; Product sales: REVLIMID: $5.8B (+16%), ABRAXANE: $967M (+14%), POMALYST/IMNOVID: $983M (+45%) and OTEZLA: $472M.
    • Preliminary Q4 results: non-GAAP EPS: ~$1.18; GAAP EPS: $0.63 - 0.73.
    • Concurrently, the company announces changes to its senior management team effective March 1. Chairman & CEO Bob Hugin will transition to Executive Chairman, President & COO Mark Alles will be promoted to CEO, President, Global Hematology and Oncology Jacqualyn Fouse, Ph.D., will be promoted to President & COO and Scott Smith, President Immunology & Inflammation will assume an expanded leadership role.
    | Mon, Jan. 11, 12:24 PM | 9 Comments
  • Dec. 23, 2015, 9:12 AM
    | Dec. 23, 2015, 9:12 AM | 7 Comments
  • Dec. 22, 2015, 6:41 PM
    • Celgene (NASDAQ:CELG) is up 6.9% after hours following a patent settlement concerning its top-selling drug, Revlimid.
    • The drugmaker's deal with India's Natco Pharma and its U.S. partner Arrow International (part of AGN) means Natco and Arrow get a license to make an unlimited quantity of generic Revlimid starting Jan. 31, 2026 -- more than a year before patents on the drug expire (April 2027).
    • Natco will also get a limited license to sell the multiple myeloma drug -- which made up 63% of Celgene's $2.3B in revenues last quarter -- in the U.S. starting March 2022.
    • Jefferies on the deal: "Though this represents a compromise, overall we view the settlement as a positive, removing a major overhang on shares and enabling a clearer road towards lower-risk long-term growth."
    | Dec. 22, 2015, 6:41 PM | 17 Comments
  • Dec. 22, 2015, 5:39 PM
    • Top gainers, as of 5.25 p.m.: CELG +9.4%. CLNE +2.5%. DNR +4.5%. ODP +2.3%. NKE +1.9%.
    • Top losers, as of 5.25p.m.: MU -4.9%. ENPH -4.0%. TVIX -2.8%. TRN -2.8%. TICC -2.5%.
    | Dec. 22, 2015, 5:39 PM | 6 Comments
  • Nov. 5, 2015, 8:10 AM
    • Celgene (NASDAQ:CELG) Q3 results ($M): Total Revenues: 2,334.1 (+17.8%); Net Product Sales: 2,312.6 (+18.2%).
    • Net Income: (34.1) (-106.7%); EPS: (0.04) (-106.6%); Non-GAAP EPS: 1.23 (+26.8%); CF Ops: 285 (-68.4%). Earnings down due to upfront collaboration expenses led by Juno Therapeutics.
    • Key Product Sales: Revlimid: 1,453.5 (+11.8%); Abraxane: 229.9 (+8.3%); Pomalyst/Imnovid: 256.5 (+41.6%); Vidaza: 147.6 (-6.5%); Otezla: 138.7 (+688.1%).
    • 2015 Guidance: Net Product Sales: $9.0B - 9.5B (unch); Revlimid sales: ~$5.8B from $5.6B - 5.7B; Abraxane sales: $950M - 1.0B from $1.0B - 1.25B; EPS: $2.02 - 2.24 from $2.17 - 2.46; Non-GAAP EPS: 4.75 - 4.85 (unch).
    • Shares are down 4% premarket on increased volume.
    | Nov. 5, 2015, 8:10 AM | 10 Comments
  • Oct. 21, 2015, 1:22 PM
    • As if anyone following biotechs needs reminding, sellers are overwhelming the space. The iShares Nasdaq Biotechnology ETF (IBB -2.8%) is down 6% since Monday.
    • Key tickers: (BIB -6.5%)(BIS +6.3%)(VRX -38.5%)(AGN -5.9%)(BIIB -0.1%)(AMGN -1.7%)(GILD -1%)(CELG -2%)
    | Oct. 21, 2015, 1:22 PM | 66 Comments
  • Oct. 13, 2015, 3:49 PM
    • Getting out in front of what should be more bashing of their business models at the Democratic debate tonight, the healthcare names (XLV -1.3%) have about doubled the decline in the S&P 500. Within healthcare, it's the biotechs (IBB -3.1%) and pharmaceuticals (XPH -3.2%) leading the way south.
    • Celgene (CELG -3.3%), Biogen (BIIB -3.6%), Amgen (AMGN -3.5%), Allergan (AGN -4.1%), Mylan (MYL -3.6%)
    • The biotech heavy Russell 2000 (IWM -1.4%) is feeling the pain as well.
    • ETFs: IBB, IYH, XLV, XBI, VHT, PJP, BBH, FBT, HQH, CURE, XPH, HQL, PBE, FXH, RXL, IHE, FHLC, SBIO, PPH, RYH, BBC, THQ, BBP, RXD, LABU, LABD, UBIO, ZBIO
    | Oct. 13, 2015, 3:49 PM | 27 Comments
  • Sep. 30, 2015, 12:49 PM
    • Bruised and battered biotech investors get some welcome buying today as bargain hunters open their wallets. The iShares Nasdaq Biotech Index Fund (IBB +2%) is up nicely, albeit on average volume.
    • Key tickers: (AMGN +1.6%)(BIIB +2.5%)(GILD +1%)(CELG +0.7%)(DEPO +12.4%)(HZNP +8.6%)(NVO +0.7%)(AGN +4.9%)(VRX +6.4%)(REGN +0.9%)(TEVA +2%)(SHPG +2.6%)
    | Sep. 30, 2015, 12:49 PM | 26 Comments
  • Sep. 25, 2015, 3:07 PM
    | Sep. 25, 2015, 3:07 PM | 134 Comments
  • Sep. 23, 2015, 7:59 AM
    • OncoGenex Pharmaceuticals' (NASDAQ:OGXI) experimental apatorsen (OGX-427), in combination with Celgene's (NASDAQ:CELG) Abraxane (paclitaxel) and gemcitabine, failed to show a treatment benefit compared to Abraxane and gemcitabine alone in a Phase 2 clinical trial in treatment-naive metastatic pancreatic cancer patients. The results of the study, called Rainier, will be presented by sponsor Sarah Cannon Research Institute at a future medical conference.
    • CEO Scott Cormack says, "While we are disappointed with the Rainier results, we also recognize the challenges associated with developing effective treatments for such a lethal and complex disease. We remain confident in our broader apatorsen program, which includes ongoing Phase 2 clinical trials in lung, prostate and bladder cancers."
    • Apatorsen is a once-weekly intravenous drug designed to inhibit heat shock protein 27 (Hsp27), an intracellular protein that helps cancer cells survive.
    • There are ~340K new cases of pancreatic cancer each year worldwide. Most patients die within the first year of diagnosis. The five-year survival rate is less than 10%.
    • Shares are off 18% premarket on increased volume.
    | Sep. 23, 2015, 7:59 AM | 1 Comment
  • Aug. 4, 2015, 8:12 AM
    • As permitted under its 2009 Collaboration and Option Agreement with GlobeImmune (NASDAQ:GBIM), Celgene (NASDAQ:CELG) exercises its option to exclusively license GI-6207, a product candidate developed with GlobeImmune's proprietary Tarmogen platform. GI-6207, the second Tarmogen-derived product candidate licensed to Celgene, targets cancers that express carcinoembryonic antigen (CEA). It is currently in Phase 2 development for medullary thyroid cancer (MTC) at the National Cancer Institute. Top-line results are expected in H2 2016.
    • CEA is over-expressed in various human epithelial cancers, including MTC. Preclinical studies showed that GI-6207 could induce an immune response to CEA as well as therapeutic anti-tumor responses. In an earlier Phase 1 trial of monotherapy GI-6207, 20% (n=5/25) of subjects receiving the drug experienced stable or decreased levels of CEA and stable disease.
    • Under the terms of the agreement, GlobeImmune will receive an option exercise payment of $1.9M, regulatory- and sales-based milestones and royalties on commercial sales.
    • There are ~500K new cancer cases each year in the U.S. characterized by the over-expression of CEA.
    • Update: GBIM is up 46% premarket on light volume. CELG is up a fraction.
    | Aug. 4, 2015, 8:12 AM
  • Jul. 15, 2015, 10:36 AM
    • Celgene's (CELG +9.5%) $7.2B deal for Receptos (RCPT +10.3%) is “a great acquisition at a great price," Nomura analysts say, as ozanimod could enable CELG's inflammation and immunology franchise to double peak sales to $10B and reduce reliance on Revlimid to drive future growth, and the acquisition price of less than 2x peak sales is a steep discount relative to recent comparisons.
    • Wedbush analyst Liana Moussatos sees plenty of potential upside to justify a rival bidder stepping in for RCPT, noting that she had estimated the company could be valued at $348/share, or ~$10.9B, in a buyout, substantially more than CELG's $232 offer.
    • The deal is boosting some biotech names (IBB +1.9%), including PTC Therapeutics (PTCT +11.7%), Celsion (CLSN +7.1%) and Arena Pharmaceuticals (ARNA +6.7%).
    | Jul. 15, 2015, 10:36 AM | 23 Comments
Company Description
Celgene Corp is a biopharmaceutical company. It is engaged in the discovery, development and commercialization of therapies designed to treat cancer and immune-inflammatory related diseases.
Sector: Healthcare
Industry: Biotechnology
Country: United States