Tesaro (TSRO) - NASDAQ
  • Fri, Jul. 22, 8:31 AM
    • OncoSec Medical (NASDAQ:ONCS) initiated with Buy rating and $6 (253% upside) price target by Rodman & Renshaw.
    • Invivo Therapeutics Holdings (NASDAQ:NVIV) initiated with Buy rating and $23.25 (254% upside) price target by Ladenburg Thalmann.
    • TESARO (NASDAQ:TSRO) initiated with Outperform rating and $105 (14% upside) price target by Baird.
    • Selecta Biosciences (Pending:SELB) initiated with Buy rating and $23 (64% upside) price target by Stifel Nicolaus.
    • Syros Pharmaceuticals (NASDAQ:SYRS) initiated with Neutral rating and $10 (11% downside risk) price target by H.C. Wainwright.
    • Voyager Therapeutics (NASDAQ:VYGR) initiated with Buy rating and $33 (161% upside) price target by Stifel Nicolaus.
    • AveXis (NASDAQ:AVXS) initiated with Market Perform rating by Wells Fargo.
    • Celgene (NASDAQ:CELG) initiated with Buy rating and $150 (40% upside) price target by Stifel Nicolaus.
    • ReWalk Robotics (NASDAQ:RWLK) initiated Overweight rating and $10 (49% upside) price target by Piper Jaffray.
    | Fri, Jul. 22, 8:31 AM
  • Fri, Jul. 1, 10:28 AM
    • GlaxoSmithKline (NYSE:GSK) upgraded to Buy from Neutral by Citigroup. Price target is 1800p (14% upside).
    • Alexion Pharmaceuticals (NASDAQ:ALXN) upgraded to Buy from Neutral by Citigroup. Price target is $154 (29% upside).
    • IPG Photonics (NASDAQ:IPGP) upgraded to Buy from Hold by Canaccord Genuity. Price target raised to $90 (13% upside) from $85.
    • Centene (NYSE:CNC) upgraded to Overweight from Equal Weight by Morgan Stanley. Price target raised to $86 (21% upside) from $84.
    • Pacira Pharmaceuticals (NASDAQ:PCRX) downgraded to Hold from Buy by Brean Capital.
    • TESARO (NASDAQ:TSRO) downgraded to Hold from Buy by Jefferies.
    • Esperion Therapeutics (NASDAQ:ESPR) downgraded to Equal Weight from Overweight with a $13 (26% upside) price target (from $28) by Barclays. Downgraded to Neutral from Overweight with a $15 (46% upside) price target (from $50) by JPMorgan. Downgraded to Underperform from Neutral with a $10 (0% upside) price target (from $23) by Credit Suisse.
    • HeartWare International (NASDAQ:HTWR) downgraded to Market Perform from Outperform by Wells Fargo. Downgraded to Neutral from Buy with a $58 (0% upside) price target (from $60) by SunTrust Robinson Humphrey.
    • Regulus Therapeutics (NASDAQ:RGLS) downgraded to Market Perform from Outperform by BMO Capital. Price target lowered to $4 (30% upside) from $16.
    • HealthSouth (NYSE:HLS) downgraded to Underweight from Equal Weight by Barclays. Price target lowered to $42 (8% upside) from $45.
    • SciQuest (NASDAQ:SQI) downgraded to Market Perform from Outperform by Raymond James.
    • Quest Diagnostics (NYSE:DGX) downgraded to from Neutral to Sell by Jyske Bank.
    | Fri, Jul. 1, 10:28 AM | 5 Comments
  • Thu, Jun. 30, 9:42 AM
    • TESARO (TSRO -3.6%announces the initiation of an underwritten public offering of $300M of common stock. Price, volume and terms have yet to be released.
    • Update: On July 1, the company announced that its offering is 4.65M shares of common stock at $81/share. Underwriters over-allotment is an additional 697.5K shares. Net proceeds should be ~$355.6M. Closing date is July 7. Yesterday's close was $84.12.
    | Thu, Jun. 30, 9:42 AM | 3 Comments
  • Wed, Jun. 29, 12:46 PM
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  • Wed, Jun. 29, 11:10 AM
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  • Wed, Jun. 29, 9:16 AM
    | Wed, Jun. 29, 9:16 AM | 3 Comments
  • Wed, Jun. 29, 9:05 AM
    • TESARO (NASDAQ:TSRO) is up 69% premarket on robust volume in response to its announcement of positive results in a Phase 3 clinical trial, NOVA, assessing PARP inhibitor niraparib in women with ovarian cancer, including those who are germline BRCA mutation carriers and those who are not germline BRCA carriers but who have homologous recombination deficient (HRD) tumors [as determined by Myriad Genetics' (NASDAQ:MYGN) myChoice HRD test].
    • NOVA was a ~500-subject, double-blind, placebo-controlled study in patients with recurrent ovarian cancer who were in response to their most recent platinum-based chemotherapy.
    • Patients treated with niraparib experienced median progression-free survival (PFS) of 21.0 months compared to 5.5 months for placebo (p<0.0001) with 62% less risk of dying in the study period (hazard ratio = 0.38).
    • The most common treatment-emergent grade 3 (serious) or grade 4 (disabling or life threatening) adverse events were thrombocytopenia (28.3%), anemia (24.8%) and neutropenia (11.2%). The discontinuation rate was 14.7% for niraparib versus 2.2% for placebo.
    • There is no currently approved therapy in the U.S. for maintenance treatment of patients with recurrent ovarian cancer following response to platinum.
    • The company plans to file regulatory submissions in the U.S. and Europe in Q4.
    | Wed, Jun. 29, 9:05 AM | 6 Comments
  • Fri, Jun. 3, 7:37 AM
    • Bayer (OTCPK:BAYRY) and Espoo, Finland-based Orion expand their 2014 agreement to jointly develop BAY-1841788 (ODM-201) in prostate cancer, currently in Phase 3 development (ARAMIS study) for the treatment of high-risk non-metastatic castration-resistant prostate cancer.
    • The new indication will be for the treatment of newly diagnosed metastatic hormone-sensitive prostate cancer, in combination with docetaxel, in men who are starting first-line hormone therapy.
    • A Phase 3 study, called ARASENS, will begin enrolling patients in late Q4. The double-blind, placebo-controlled trial will randomize ~1,300 subjects 1:1 to receive either BAY-1841788 (ODM-201) or placebo in combination with an androgen deprivation therapy of the investigator's choice started no more than 12 weeks before randomization. The primary endpoint is overall survival.
    • BAY-1841788 is an oral androgen receptor antagonist.
    • Prostate cancer-related tickers: (NASDAQ:MDVN)(OTCPK:ALPMY)(NYSE:VRX)(NASDAQ:TTHI)(NASDAQ:EDAP)(NASDAQ:TKAI)(NYSE:JNJ)(NASDAQ:TSRO)(NYSE:AZN)(NASDAQ:EGRX)(NASDAQ:OGXI)
    | Fri, Jun. 3, 7:37 AM
  • Fri, May 20, 7:32 AM
    • Arrowhead Pharmaceuticals (NASDAQ:ARWR) initiated with Buy rating and $12 (140% upside) price target by Chardan Capital.
    • Amicus Therapeutics (NASDAQ:FOLD) initiated with Buy rating and $10 (45% upside) price target by Bank of America.
    • Quorum Health (NYSE:QHC) initiated with Equal Weight rating and $12 (2% upside) price target by Morgan Stanley.
    • TESARO (NASDAQ:TSRO) initiated with Outperform rating and $56 (30% upside) price target by Credit Suisse.
    • Prothena (NASDAQ:PRTA) initiated with Overweight rating and $60 (47% upside) price target by Barclays.
    • Mazor Robotics (NASDAQ:MZOR) upgraded to Outperform from Market Perform by Wells Fargo. Price target raised to $15-17 (14% upside from midpoint) from $10-13.
    • Eli Lilly (NYSE:LLY) upgraded to Strong Buy with a price target of $88.67 (19% upside) by the Vetr Community.
    • Haemonetics (NYSE:HAE) upgraded to Neutral from Sell by Goldman Sachs. Price target raised to $29 (5% upside) from $25.
    • Nanosphere (NASDAQ:NSPH) downgraded to Neutral from Buy by Rodman & Renshaw. Price target lowered to $1.35 (2% upside) from $2.00.
    • Anacor Pharmaceuticals (NASDAQ:ANAC) downgraded to Neutral from Buy by Mizuho Securities. Price target set at $99.25 (0% upside).
    • Globus Medical (NYSE:GMED) downgraded to Sell from Neutral by Goldman Sachs. Price target lowered to $21 (10% downside risk) from $26.
    • EPIRUS Biopharmaceuticals (NASDAQ:EPRS) downgraded to Market Perform from Outperform by Leerink Swann. Price target lowered to $0.75 (27% upside).
    | Fri, May 20, 7:32 AM | 10 Comments
  • Thu, May 5, 4:42 PM
    • Tesaro (NASDAQ:TSRO): Q1 EPS of -$2.22 misses by $0.53.
    • Revenue of $0.31M misses by $2.17M.
    • Press Release
    | Thu, May 5, 4:42 PM
  • Wed, May 4, 5:35 PM
  • Wed, Apr. 6, 7:50 AM
    • Johnson & Johnson's (NYSE:JNJ) Janssen Biotech inks a license and collaboration deal with TESARO (NASDAQ:TSRO) for exclusive global rights, except Japan, to develop and commercialize poly polymerase (PARP) inhibitor niraparib for the treatment of prostate cancer.
    • Under the terms of the agreement, TESARO will receive an upfront payment, milestones and royalties on net sales. Specific financial terms are not disclosed.
    • Separately, Johnson & Johnson Innovation, J&J's venture capital arm, will make an equity investment in TESARO.
    • PARP proteins play a key role in DNA repair in cancer cells. Inhibiting PARP prevents certain defective cancer cells from repairing themselves which leads to cell death. A portion of men will prostate cancer have these defective cancer cells and may benefit from treatment with a PARP inhibitor.
    • Niraparib is an orally administered PARP inhibitor also under development for the treatment of metastatic breast cancer and ovarian cancer.
    | Wed, Apr. 6, 7:50 AM
  • Fri, Mar. 18, 11:38 AM
    • Applied Genetic Technologies (AGTC +0.8%) initiated with Buy rating with $25 (85% upside) price target by Janney Capital.
    • Nomura's Ed Ridley has been busy in devices. He rates the following companies a Buy: Boston Scientific (BSX +1%) PT: 22 (22% upside); Zimmer Biomet Holdings (ZBH +0.3%) PT: 123 (18% upside); Edwards Lifesciences (EW +0.8%) PT: 101 (19% upside); St. Jude Medical (STJ +0.5%) PT: 64 (19% upside); Stryker (SYK +0.7%) PT: 115 (6% upside); Medtronic (MDT +0.8%) PT: 86 (13% upside). He rates C.R. Bard (BCR +0.7%) Neutral with a PT of $205 (5% upside).
    • Tesaro (TSRO +2.6%) initiated with Buy rating and $65 (46% upside) price target by Citigroup.
    • CRH Medical (CRHM +0.1%) initiated with Buy rating and $5 (48% upside) price target by Canaccord Genuity.
    • Evoke Pharma (EVOK) initiated with an Outperform rating and $16 (258% upside) price target by Northland Securities.
    • NanoString Technologies (NSTG -0.2%) initiated with Buy rating and $21 (31% upside) price target by Janney Capital.
    • AbbVie (ABBV +0.6%) initiated with Hold rating and $63 (13% upside) price target by Deutsche Bank.
    | Fri, Mar. 18, 11:38 AM | 5 Comments
  • Thu, Feb. 25, 4:13 PM
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Company Description
TESARO, Inc. is an oncology-focused biopharmaceutical company. It is dedicated to improving the lives of cancer patients. The company's product portfolio currently consists of three oncology-related product candidates: Rolapitant, Niraparib and TSR-011. TESARO was founded by Leon Moulder, Jr.,... More
Sector: Healthcare
Industry: Biotechnology
Country: United States