Immtech Intl, Inc. (IMM)

All Comments on IMM

  • commenter
    pbd@entheolo
    gic.com
    Apr 22 07:36 PM
    My Website
    Immtech Drops on Halted Clinical Trials [view article]
    ABSTRACT: The pharmaceutical development of pafuramidine (DB289) as an orally administered antimicrobial diamidine prodrug was discontinued by Immtech Pharmaceuticals, Inc. (Amex:IMM) on February 22, 2008 because of unexplained idiosyncratic drug induced organ toxicity (IDIOT). The unexpected IDIOT seen in a recent Phase I safety study can be explained in terms of the mechanism of action (MOA) for pafuramidine and in view of differential drug absorption, distribution, metabolism and excretion (ADME) as between healthy subjects and infected patients. Human healthy subjects (volunteers) are NOT appropriate subjects for testing the safety of an oral pafuramidine dosing protocol that ultimately will be used to treat patients that have serious infections (such as African sleeping sickness, PCP or malaria). The ADME for healthy volunteers should be different than for infected patients. Healthy subjects should absorb more pafuramidine relative to infected patients and therefore be at a higher risk of drug induced organ toxicity. The maximum tolerated dose (MTD) of oral pafuramidine that will be safe and effective for treating seriously infected patients probably will NOT be safe (as safe) when tested in health volunteers.
    pbd@entheologic.com     Reply
  • commenter
    SeekingAlpha
    Editors
    Apr 06 05:22 AM
    My Website
    General Discussion on IMM
    Is this a buy or a sell? Reply
  • commenter
    Richard Shaw
    Apr 04 01:52 PM
    My Website
    The Ins and Outs of Terror-Free Investing [view article]
    Mr. Potato Head,

    You view is similar to mine as expressed in a follow-up article:

    www.qvmgroup.com/inves.../

    Richard Shaw

     Reply
  • commenter
    User 53132
    Apr 04 12:26 PM
    The Ins and Outs of Terror-Free Investing [view article]
    Mr. Shaw

    Terror-free investing as a national policy might or might not work. The unilateral decisions of the US haven't worked out very well e are the best electronics designed and manufactured? Not in our clately, but lets put that aside.

    Who decides what is a terror state? Could China be on that list because of its policies in Tibet? What about Russia and the disappearance of its citizens? What about the US in Iraq and Afghanistan; aren't we terrorizing part of their populations? Is the decision made by someone stuck at a desk in the corner who's name and character are unknown? Maybe we could make it with decisions of congress?

    If everything goes OK, who moves in when we move out? The French, Russia, China? How about Venezuela? Maybe North Korea?
    Wouldn't it be a welcome change to see North Koreans helping out Pakistani Citizens with all their nuclear needs?

    The economic and political power of the US is dwindling as other countries of the world move toward the center stage. Where are the fastest grown economies? Which countries are graduating the most engineers, scientists, and business majors? Where are the best and newest examples of architecture? Not in our country.


    For terror free investing to work on a global scale would require the combined efforts of several independent nations. The US will need to find a new attitude of pragmatism and co-operation as its influence diminishes over the coming decades.

    However, everything else aside, the idea has merit. On an individual basis, or perhaps dedicated "terror free" fund, we could give it a try.

    Mr Potato Head     Reply
  • commenter
    Jimk7
    Dec 30 05:03 AM
    China Biotech Week in Review: East-West Interdependence in 2007 [view article]
    A lot of U.S. bio-pharma companies are taking stakes in established entities listed on the Hong Kong exchange. Though we probably won't see pops like we would in Chinese companies listed in the U.S. It could be something to gamble on for the long-term. You can pick them up for pennies on the dollar per share but most of the time are required to buy in blocks of thousands. Reply
  • commenter
    Mary Ellen
    Stevens
    Jul 12 01:21 PM
    The Ins and Outs of Terror-Free Investing [view article]
    MPVALUCH

    Thanks for responding. The fact is that the article does not "slam" any company.
    The article simply reports on the actions of the government and the issues floating around among states and others to try to get a handle on this particular form of social investing that is also being driven in part by government actions.

    The article takes no position on any company and does not take a position on whether terror-free investing is a good or bad idea, helpful or hurtful for international outcomes, or suitable or unsuitable for any person. The article reports on the phenomenon and does not promote the matter one way or the other.

    You have misread the article and might look at it once again to see that no opinion is expressed about any company.

    If anything, the article suggests that the process might in fact create some undesirable to unjust outcomes in the implementation.

    You are certainly correct that SEC filings are historical and SEC reviews of filings take some time after the filing, so it is highly likely that the SEC will continue to list certain companies for a limited period of time as having operations that may have been discontinued.

    Sorry the article was upsetting to you, but your emotional reaction is misplaced. If you have concerns about how the SEC does its work, you might direct your concerns to them and not to those who report on the work of the SEC.

    Richard Shaw
    QVM Group LLC     Reply
  • commenter
    mpvaluch
    Jul 12 11:25 AM
    The Ins and Outs of Terror-Free Investing [view article]
    Mr. Shaw,

    Maybe you should include that the SEC used a simplistic approach when creating this list! Reuters reported this on July 5th, but apparently you missed it:

    www.reuters.com/articl...

    BHI has had no operations in Sudan since 2005---but because that fact was mentioned in its 2006 annual report, it got included in the SEC's list. How many other companies will unnecessarily get slammed today because of your submission? Hmmmm!?

    mpvaluch     Reply
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