Oct. 19, 2014, 6:37 PM
Oct. 7, 2014, 11:57 AM
- BC, Canada-based Xenon Pharmaceuticals (XENE) is set for its IPO of 4M shares at $10 -12.
- The clinical-stage biopharmaceutical firm discovers and develops differentiated therapeutics for orphan indications based on its Extreme Genetics platform. It focuses its discovery efforts on rare human diseases with extreme traits, including diseases caused by mutations in ion channels.
- The Extreme Genetics platform yielded the first gene therapy product approved in the EU, uniQure's (QURE +1.5%) Glybera (alipogene tiparvovec) for the treatment of adult patients with familial lipoprotein lipase deficiency.
- Its pharma partners include (TEVA -0.3%), Genentech (OTCQX:RHHBY -2.5%) and Merck (MRK -1.2%). Collaborations have generated over $140M in revenue to Xenon so far. Future milestone payments could potentially surpass $1B.
- The company's lead product is TV-45070 for the treatment of osteoarthritis of the knee. A 300-patient Phase 2b clinical trail run by Teva subsidiary Ivax International GmbH is underway.
- A second product candidate, GDC-0276, for the treatment of pain is being developed in collaboration with Genentech. A Phase 1 study commenced in September 2014.
- Osteoarthritis of the knee-related tickers: (AMPE +0.3%)(FLXN -4.6%)(ANIK -1.2%)(ZMH -0.7%)
Sep. 1, 2014, 10:59 AM
- Zimmer Holdings (NYSE:ZMH) will hear back from EU antitrust authorities by Oct. 3 over whether or how it will be allowed to pursue its $13.4B takeover of rival Biomet (Pending:BMET).
- Zimmer originally sought approval in June, but the EU regulator paused the review because the company's submission was lacking details.
Aug. 26, 2014, 7:16 AM
Jul. 24, 2014, 1:04 PM
- Zimmer Holdings (ZMH -3.5%) Q2 results: Net Sales: $1,182.9M (+1.1%), Reconstructive: $890.4M (+2.6%), Dental: $61.1M (-0.5%), Trauma: $78.8M (+6.3%), Spine: $52.2M (-3.7%), Surgical & Other: $100.4M (-10.2%); COGS: $333.2 (+3.0%); Gross Profit: $849.7M (+0.4%); R&D Expense: $48.1M (-12.4%); SG&A Expense: $455.8M (0.5%); Operating Income: $259.3M (+23.2%); Net Income: $176.1M (+16.1%); EPS: $1.03 (+15.7%); Quick Assets: $1,698.0M (-6.1%); CF Ops (1H): $442.9M (+19.6%).
- 2014 Guidance: revenue growth: 2.0 - 3.0% from 3.0 - 5.0%; diluted GAAP EPS: $4.65 - 4.75 from $4.90 - 5.10; diluted non-GAAP EPS: $6.00 - 6.10 from $6.00 - 6.20.
Jul. 24, 2014, 7:37 AM
May 23, 2014, 7:04 AM
Apr. 24, 2014, 12:46 PM
Apr. 24, 2014, 9:28 AM
Apr. 24, 2014, 7:43 AM
- Zimmer (ZMH) says the transaction will "position the combined company as a leader in the $45B musculoskeletal industry," adding that "the complementary nature of the two businesses adds diversity and scale across various geographies and product categories."
- Zimmer expects the purchase to be "double-digit accretive" to its EPS in the first year after closing, and to boot its cash flow from operations by 1.5 times. The company also forecasts annual synergies of $135M in the first year and $270M by the third year.
- The combined 2013 revenues of the companies were $7.8B and adjusted EBITDA was $2.8B.
- Zimmer will pay $10.35B in cash and the rest in shares. The company will help fund the deal with a $3B senior unsecured term loan and newly issued senior notes.
- Zimmer shares continue to climb and are +11.5%. (PR)
- Zimmer Q1 earnings
Apr. 24, 2014, 7:21 AM
Apr. 24, 2014, 7:20 AM
Apr. 15, 2014, 6:25 PM
- Surgical device maker ConMed (CNMD) is exploring a sale of the company, Reuters reported earlier today, after activist investors late last year took issue with its performance and corporate governance.
- The company's advisers, BoA Merrill Lynch and Greenhill, reportedly have contacted orthopedic device makers in recent weeks to gauge interest.
- CNMD has an attractive orthopedics and sports medicine business that could appeal to companies such as Zimmer Holdings (ZMH), Johnson & Johnson (JNJ), Stryker (SYK), Covidien (COV) and Medtronic (MDT).
- CNMD shares gained 7.2%, rallying from a loss before the report late in the session.
Mar. 5, 2014, 5:15 PM
Feb. 26, 2014, 9:43 AM
- Anika Therapeutics (ANIK) surges 41% to $48.67 following the FDA's approval of the company's Monovisc single injection for pain caused by osteoarthritis of the knee.
- The authorization must feel pretty sweet for Anika - it first applied for approval over four years ago.
- Summer Street has hiked its price target to $60 a share from a prior PT of $47.
- "We believe this product will be competitive in a market that is becoming more focused on single-shot injections," Summer Street says.
- There are 27M people in the U.S. who suffer from osteoarthritis, which occurs when cartilage breaks down in joints, causing pain and stiffness as bones rub together.
- Sanofi (SNY +0.1%) and Zimmer (ZMH +0.4%) sell rival products.
Jan. 30, 2014, 7:32 AM| Comment!
ZMH vs. ETF Alternatives
Zimmer Holdings Inc designs, develops, manufactures and markets orthopaedic reconstructive, spinal and trauma devices, biologics, dental implants and related surgical products. It also provides other healthcare related services.
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