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  • Oncolytics: Killing Cancer With A Virus [View article]
    see CFRX; precisely that intent
    Jul 21, 2015. 01:04 PM | Likes Like |Link to Comment
  • MannKind: Decision Time Regarding Those Convertible Bonds [View article]
    Might MNKD change the conversion terms to make that route more attractive to bond holders? Money in the coffers and dilution would be minimal.
    Jul 15, 2015. 09:17 PM | Likes Like |Link to Comment
  • My Primary Care Provider's Take On Afrezza [View article]
    As part of a group practice I assume there would be some buzz about new treatments. I wonder if your nurse practitioner would be swayed by opinions of her colleagues who had used Afrezza (prior to the 1-2 year point).
    May 19, 2015. 09:29 PM | 1 Like Like |Link to Comment
  • The United States Economy Is Not Really Doing That Well [View article]
    ...the juveniles that run Greece??? Please. How about some mention of those in northern Europe not to mention those a little closer to home?
    Mar 14, 2015. 03:53 PM | Likes Like |Link to Comment
  • The ECB's Noose Around Greece: How Central Banks Harness Governments [View article]
    Thanks for another excellent piece. You might consider discussing this as an example of early phase rope a dope strategy:
    Mar 12, 2015. 08:40 AM | Likes Like |Link to Comment
  • The Confiscation Of Bank Deposits And The Derivative Debt: James Corbett Interviews Ellen Brown On GRTV (Video) [View article]
    Gee, try as I may I just can't imagine a purpose for someone to repeat ad nauseum hackneyed talking points that conflate policy as is -- whereby private owners receive and divert from public hands all interest and profits on public banking business, put public funds in jeopardy via risky investment activity and influence our political system so as to maintain / enhance that position -- with publicly-owned, apolitical, accountable, transparent, simple depository institutions whose profits accrue to their public owners, i.e., citizens of the state (or county, city, etc.).

    My previous comments stand.

    May I again suggest that anyone wishing to pursue the concepts static-free read The Public Bank Solution and Web of Debt.
    Jan 4, 2015. 08:26 PM | 1 Like Like |Link to Comment
  • The Confiscation Of Bank Deposits And The Derivative Debt: James Corbett Interviews Ellen Brown On GRTV (Video) [View article]
    @Jim Myrtle 7:23PM 1/3/15 comment
    Sorry, no again. A public bank would be federally chartered just like a private bank with directors, officers and employees with the same fiduciary responsibilities and oversight. What incentive would they have to promote particular politicians - to promote the depository banking agenda? I can't think of too many pressing issues there, it is not sexy or even wildly profitable (It is only profitable without superlative-type adjectives, and quite safe) which is why the private megabanks have largely migrated to other profit centers. That, and perhaps something written into the charter forbidding political donations, would effectively limit political kowtowing. The laundry list of malinvestments / mal-lending that you provided is precisely what a conservative bank chartered for the purpose of public rather than private good would resist. In addition, interest (e.g., on CA's $54B essentially untouchable rainy day fund mentioned in the interview which would be kept in the federally chartered bank owned by CA) would now be available as profit to the public for public benefit, and assets like taxes collected but not yet spent, kept in a public depository-only bank rather than a private TBTF bank, at the very least would not be exposed to derivative risk.

    A public bank would not eliminate private banks it would function alongside them handling mainly public funds and doing some public works-related lending in the manner of other depository institutions.

    Your statements re: foibles of public banks actually pertain to incentives currently in place for private banks. That public banks would divert cash flow from private banks is a powerful incentive for private bank interests to quash the notion, wouldn't you say? Could any of the more shrill objectors to this interview be of the latter bent?

    If Glass-Steagall-type legislation is not to be, then besides modifying the flow of publicly paid interest to support public coffers rather than private, publicly owned banks are a means of protection of public assets from private whoops and/or greed.

    Read The Public Bank Solution. It is accessible and very clearly written. And the unfamiliar should also read Web of Debt which is a similarly clear treatment of money creation and debt.
    Jan 4, 2015. 09:42 AM | 2 Likes Like |Link to Comment
  • The Confiscation Of Bank Deposits And The Derivative Debt: James Corbett Interviews Ellen Brown On GRTV (Video) [View article]
    @Bill Cunningham-
    Have airlines hedged against the possibility of lower oil prices?
    Jan 3, 2015. 06:04 PM | Likes Like |Link to Comment
  • The Confiscation Of Bank Deposits And The Derivative Debt: James Corbett Interviews Ellen Brown On GRTV (Video) [View article]
    @Jim Myrtle,
    no, not in the hands of politicians, in the hands of publicly accountable, transparent boards of governors who are responsible for obeying all depository banking rules and regs just like private banks. you actually have it backwards. public banks take the money (as in electoral campaign contributions and the like) out of the hands of politicians.
    Jan 3, 2015. 06:02 PM | Likes Like |Link to Comment
  • The Confiscation Of Bank Deposits And The Derivative Debt: James Corbett Interviews Ellen Brown On GRTV (Video) [View article]
    @Lakeaffect -
    From the treatment they received after 2008 what lesson were the too big to fail banks supposed to learn?
    Jan 3, 2015. 05:59 PM | Likes Like |Link to Comment
  • One Internist's Glance At MannKind's Afrezza [View article]
    This was a credible attempt to view Afrezza through the lens of the current diabetes treatment paradigm, for which the author should be commended, and many of the comments both agreeing and disagreeing were cogent as well. The problem is that Afrezza's place in diabetes treatment will remain unknowable until insight is gained from real world use rather than attempts to extrapolate from data provided by clinical trial protocols. The current treatment paradigm could be completely upended or greatly extended as has happened with many diseases recently for which new concepts have appeared (e.g., rheumatoid and other inflammatory arthritides, inflammatory bowel diseases, asthma, chronic hives, various cancers, various heart maladies, etc.). Experience with Afrezza may demonstrate more or less efficacy than current modalities, more or less side effects, pulmonary toxicity or no significant pulmonary toxicity, contraindication for otherwise-ill patients (who are excluded from drug trials as a rule) or no contraindication, contraindication in stable asthmatics or not, unsuitability for smokers or not, etc. etc. Will it matter that absorption is delayed by a few minutes in smokers if the total dose effect dissipates much more rapidly than injected insulin (or oral agents for that matter)? Does dose matter beyond "some" or "enough" for an agent whose effect may dissipate before it can cause harm? The point is that clinical trials are only measures of safety and efficacy and often do not provide insight into nuances of eventual clinical utility. There is potential for Afrezza to alter the current paradigm. It is just too soon to know.
    Jan 3, 2015. 01:35 PM | 12 Likes Like |Link to Comment
  • News From Sanofi About MannKind's Afrezza And Its Future [View article]
    In addition to Pycho Analyst's comprehensive answer (& thanks for the nice article P A) ...
    I have no more direct knowledge about Afrezza than anyone else outside MNKD / SNY but based on what I have seen it will enable you to eventually alter your statement "In general bolus insulin is the absolute last resort in treatment." Hesitation about using bolus insulin is because it is hard to get right, nearly impossible with a good number of patients, type I and type II, leading to over and undershooting. If it worked well, like a physiologic phase I insulin response, there would be no hesitation, right? Afrezza will change that equation. Likely fewer units will be needed than current bolus preparations because of reduced insulin resistance and physiologic action, and physiologic clearance times also will limit or perhaps remove the apprehension regarding dosing too high or eating too little or other vagaries that lead to hypoglycemia in patients who are trying their best. My opinion is that Afrezza will alter the landscape by combining nicely with no or low dose basal insulin to provide effective and safe control for a great many patients especially if they also reasonably embrace diet, exercise and weight loss. I believe once patients and family physicians - as well as specialists - appreciate this Afrezza will be very rapidly accepted.
    Nov 1, 2014. 05:27 PM | 9 Likes Like |Link to Comment
  • A Potential Game Changer In Cancer Screening [View article]
    nice piece.

    gotrocks, 84% sensitivity is at least comparable to current noninvasive routine screening methods other than colonoscopy, which in the future might be reserved for those with symptoms or at high risk or with positive screening blood test -avoiding patient discomfort and wasted time and reducing healthcare dollars. And (to play devil's advocate) even it were not quite comparable, enhanced compliance from the ease of the doc simply adding one more blood test to the routine screening panel assessing lipids, diabetes, maybe PSA, etc. every ?5 years seems to represent an improved standard of care. What remains to be shown is that sensitivity and validity hold up with future study in asymptomatic patients who would comprise the typical screening candidates. As mentioned by another commenter test tweaking could even improve expectations.
    Sep 17, 2014. 09:23 PM | 2 Likes Like |Link to Comment
  • 4 Reasons Adamis Pharmaceuticals Could Be A Multi-Bagger [View article]
    Very comprehensive article, thanks. QVAR's niche and marketing focus is its very small particle size which reaches the smaller airways. What is the particle size of APC-1000?
    May 15, 2014. 08:49 AM | 2 Likes Like |Link to Comment
  • Banking Union Time Bomb: Eurocrats Authorize Bailouts And Bail-Ins [View article]
    " It is only centuries of bankster mystification of money that prevents people from seeing how technically easy it would be to implement a truly sound public money system." That and the likelihood of corruptibility of public officials placed in control of public bank(s), abetted by the unlikelihood of sufficient monitoring and effective oversight by institutions and citizenry.
    Mar 30, 2014. 08:49 PM | 1 Like Like |Link to Comment