delta 777

Hoping Against Hope for Wyeth / Elan Alzheimer Dug

"Human beings are the only animals that really seem to get Alzheimer's, and that's made it a ferocious therapeutic area to work in"
perhaps not quite true--it appears that vervet monkeys also develop a condition as they get old that is very close to a human form of Alzheimer's. This is species specific, as rhesus monkeys do not develop this. Vervets have some other characteristics that are particularly relevant to humans.
www.dana.org/news/feat...
pin.primate.wisc.edu/f... (see special notes sections)

Elan, Wyeth Take an Inside-Out Approach to Alzheimer's Vaccine

jarcom--you say "An alzheimer vacine....simply panovian. AHP used to be smarter than to go for such stuff."-----are you perhaps suggesting that AHP was "smarter" in its fen/phen days????

Elan, Wyeth Take an Inside-Out Approach to Alzheimer's Vaccine

again, Here Derek seems to share a common confusion with respect to Elan's Alzheimer's pipeline....Right now their prime focus is on an antibody (not a vaccine) therapy identified as AAB-001 (Bapineuzimab), which anticipates important PII result announcement very soon, and full PII info at ICAD on July 30..PIII for AAB-001 has already started... Although AAB-001 is an immunologic approach, it is distinctly different and not to be confused with ACC-001 which is an antigen, or vaccine.. Elan has several other extremely promising Alzheimer's drugs in its pipeline, as well as the highly effective multiple sclerosis drug Tysabri....Elan is primarily a research biotech, and commonly partners with companies better equipped for large scale manufacturing. (which arrangementsd also, because of careful poison pill agreements, protect against easy hostile take-over)....There is a very active InvestorVillage message board with quite a few brilliant and very knowledgeable posters on Elan (significant posts can be roughly presorted based based on number of recs, then following the thread): www.investorvillage.co...