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Loneflycaster

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  • Celsion Showing Small Signs Of Life After Tanking 95% [View article]
    Why are they using RFA with its inherent limitations instead of MWA?
    Jul 31 12:15 PM | Likes Like |Link to Comment
  • It's Not About Discovering A Mine, It's About Discovering A Technology [View article]
    To the Berry's if they are looking for disruptive medical equipment technologies, look at AEMD, BSDM, EDAP & MZEI. All penny stocks at present, but with interesting technologies.
    Jun 18 02:38 PM | 1 Like Like |Link to Comment
  • EDAP TMS: 2014 FDA Decision On Treatment For Prostate Cancer Could Bring Attractive Gains [View article]
    My question: are there any disposable products being sold in conjunction with the Ablatherm system?
    Jan 22 02:04 AM | Likes Like |Link to Comment
  • 8 Reasons Why I Expect Molycorp Shares To Double In 1Q 2014 [View article]
    Mark,
    If you are in the San Francisco area, there are several option groups
    that meet on a regular basis.
    Oct 15 02:00 PM | Likes Like |Link to Comment
  • Celsion: 50% Downside After The HEAT Trial Failed [View article]
    As I understand RFA has a limit of 3 cm for tumors, but MWA is capable of ablation of 7 cm tumors in half the time. If CLSN were to start another trial wouldn't they be better off using MWA, especially the unit from BSDM that uses synchronous antennas?

    Also, if RFA has that 3 cm limit, why did CLSN use RFA for larger tumors? And isn't 45 min. a long time to use RFA considering its inherent limitations?

    Another question I have is, does the effectiveness of Doxorubicin deteriorate with high heat because as I understand T-Dox releases at much lower temperatures?
    Jun 11 04:25 PM | 2 Likes Like |Link to Comment
  • Short sales on S&P 500 stocks fall to 5.6% of shares available, according to Bespoke. It's the lowest ratio since at least 2007 and compares to a record 12% amid the financial crisis. "When you have a market where investors are all in, there will no longer be short covering," says one money manager. [View news story]
    There was a top in the stock market in 2007, so logically there is a top already formed or forming.

    Contrarily, is it time to short? My work say it is.
    Mar 4 01:20 PM | Likes Like |Link to Comment
  • Celsion Stock Blown Apart On Thermodox Phase III Data [View article]
    Brian,

    From what I see there are two possibilities for the failure.
    1. Thermodox was designed to release ~42C. Is it possible the temperature of thermal ablation is too high [~170F], and that it interfered with either the lipsomes and/or the chemo?

    "Lysolipid Thermally Sensitive Liposomes, or LTSL’s, are a unique liposomal technology that allows for the triggered release of a drug payload through low temperature (just above body temperature) heat activation. Used in combination with heat therapy, this concentrates therapy directly within the treatment area." Celsion's website.

    2. Is doxorubicin the right chemo for HCC? There was a doctor in the comments of another SA article stating that doxorubicin did not work before for HCC and would not work in the HEAT trial. I asked for clarification, but he did not answer.

    In addition, if you look at Dr. Poon's presentation that is on Celsion's website, you will see pictures showing that T-Dox works for recurrent chest wall breast cancer [RCW]. The hyperthermia machine in one of the pictrues was the BSD-500 which provides temperatures of ~42C. Celsion is nearing or has completed P-II of the DIGNITY trial for RCW, and I hope Celsion continues the DIGNITY trial into P-III.
    http://tinyurl.com/avb... Page 26.
    Feb 2 06:53 PM | 1 Like Like |Link to Comment
  • Refocused, Reframed And Patiently Awaiting Celsion's Real Results After This Week's Chaos [View article]
    Doc, please explain what you mean by "effective".
    Jan 19 01:59 PM | 2 Likes Like |Link to Comment
  • The iPhone 5 is still supply-constrained at U.S. Apple Stores, says Piper's Gene Munster after polling 70 of them. He also found ongoing shortages at AT&T and Verizon, though Sprint's situation is said to be improving. Those comments are probably contributing to today's Apple (AAPL -2.7%) selloff, especially since Munster's Oct. 4 report on shortages proved accurate. On a more positive note, Munster's poll of 730 U.S. consumers found 55% of those planning to buy a smartphone indicating they want an iPhone 5. [View news story]
    I don't understand this supply constraint bs. This is a post I made regarding my i-5 purchase on 10/9/12 through AT&T. My phone was the full-bore version so maybe the constraints are for the less endowed models.

    [10/12/2012 11:17:40 AM] Amazing, I ordered an i-5 on Tues. and was told it would take 3-4 weeks. Got a message yesterday that it was shipped on Wed.
    Nov 2 04:06 PM | 1 Like Like |Link to Comment
  • At $610, Apple Is Again A Buy [View article]
    Supply problems? I wonder because I ordered my i5 from AT&T on 10/9 with an indication of 3-4 week delivery time.

    On 10/11 I received a notice that my i5 had shipped! I received it on 10/15.

    So I am wondering, what supply problems Apple has?
    Oct 22 11:45 AM | Likes Like |Link to Comment
  • What's Wrong With These Pictures? [View article]
    Take the example of Whirlpool gobbling up Maytag which is a textbook example of the euphamistic "realization of synergies" and "cost efficiencies".

    Oh really?! bynd2009. IMO, the textbook example of Maytag is that Maytag had to sell to Whirlpool because they made a lousy product in the Neptune washer and their refrigerators. The fact that their products were bad is the reason it was bankrupting Maytag, and it would have gone bankrupt without the sell-out to WHR. I know about both of those products from personal experience. I own 49 Neptunes in my self-service laundry business, and they have been a headache ever since they were installed. In the first year I had a greater than 30% failure rate, and they continue to break down on a regular basis. The refrigerator I owned personally, and it failed in the first year.

    As far as AIG, you should rethink your bailout thesis. The money given to AIG was a pass-thru to Goldman Sacks so that Paulson's former firm could stay alive.
    Feb 15 03:16 AM | Likes Like |Link to Comment
  • How Much Natural Gas Remains in the USA? [View article]



    On Oct 04 04:22 PM User 283977 wrote:

    > Summary:
    > Proven reserves refers to natural gas that can be extracted economically
    > at current market prices.

    Huh? Proven is proven, period. Either you proved the reserves exist, or they do not. Proven reserves only change with the amount of depletion plus new proven reserves. How can this be otherwise? How can you say that X amount will be proven at a price but that Y amount will be proven at a different price?
    Oct 5 01:47 PM | Likes Like |Link to Comment
  • Friday Outlook: Commodities, Global Markets [View article]
    Michael, you can Google for Zero Hedge, or use this link.

    zerohedge.blogspot.com/
    May 23 12:27 AM | Likes Like |Link to Comment
  • 5 ETFs That Appear in the Bargain Bin [View article]
    These etf may be bargains for expense ratios, but their price trends suggest they should be avoided until they at least have a price base.
    Mar 2 02:30 AM | Likes Like |Link to Comment
  • Pipeline MLPs: A Hedge Against Market Downturn [View article]
    "Production is expected to grow at double-digit rates this year, after increasing 15% last year. Also, the recent creation of a pipeline MLP and a $1 billion buyback program are some important catalysts for future growth."

    I am mystified by your reference to a new MLP. TCLP is an MLP already. Are you referring to the new LLC, Bison Pipeline LLC?

    Also I have not seen any reference to a buy-back program in the time I have owned the units. Is this old news?

    Why do a buy-back when increasing the distribution will accomplish the same thing, i.e., increase the yield and thereby increase the value of the MLP units?
    Apr 9 06:34 PM | Likes Like |Link to Comment
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