obesejockey

Alzheimer Drug Fails Trial

You must be a glass half empty kind of guy, but Alzheimer's is a disease where the disease modifying drug glass is completely empty. The top line results indicate that perhaps half the patients can be helped with statistical significance. The placebo was Aricept. Why not wait for the full study results to be presented at ICAD on July 29 (warts and all) before drawing conclusions about the APOE carrier subgroup? One reason the phase 2 study is under powered is that the study tested several dose levels with the intent to determine the best dose level. The ongoing phase 3 study reflects what was learned in phase 2.