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  • Acura' Acurox: A Revenue-Deterrent Formulation of Oxycodone [View article]
    Name one that cannot be circumvented by taking excessive doses intact?-

    Aside from a pro-drug approach like NRP's which cannot be used for analgesics.
    Oct 06 11:53 am |Rating: 0 0 |Link to Comment
  • Acura' Acurox: A Revenue-Deterrent Formulation of Oxycodone [View article]
    Actually, this is a very well thought out article. The use of niacin as a detterent s a bone headed maneuver. Why treat all of the patients as abusers, which is what adding a pharmacological deterrent is doing? Where I think they get it wrong is that all of the tamper technologies are bypassed by taking them orally, intact. Therefore they are all faulted Take two ER 40mg to get the effect of one IR 30mg. They are right in that the FDA also will not allow label claims unless post marketing studies validate the claims. That goes for Remoxy also. Post marketing studies will take years but that helps King. I can always get 10 addicts to say that Remoxy is harder to snort than the old OxyContin. That is a study to submit. I think the key for King is to price it a cheaply as possible and pull market share.
    Aug 26 09:06 am |Rating: 0 0 |Link to Comment
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