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  • Advanced Cell Technology Annual Meeting Announcement: A Harbinger Of...? [View article]
    I beg to differ. Wet and Dry cell treatment have strong similarities -- the ability of cells to replace ( & restore) the functions of damaged cells. I did not say the Japanese were leading in their research. In fact, ACTC is ahead but not that much and will soon be surpassed because of the law passed in Japan less than a year ago that simplifies approval of stem cell treatments. The Japanese law was designed to overcome the long licensing processes that just delays unnecessarily the development and approval of treatments. They have watched what the FDA has been doing and they have instituted a legal path to simplify and speed up the process.... and still be ethical.

    ACTC has an edge, business wise. 85%-90% of AMD is the Dry type, 10-15% is Wet AMD. 90% of severe vision loss is the Wet type. In almost all cases Wet AMD starts out as Dry AMD. There is an estimated 50 million cases of AMD around the world.

    In the Japanese treatment, the damaged retina section is removed .... a difficult process .... and replaced with a section of grown iPS cells. On the other hand, Actc just injects the heSC (Trials indicate best efficacy is about 150-200,000 cells - about the volume of 3 pin heads) right into the macular area and the cells find its way to replace the damaged ones. Actual operation is only a few minutes. Waiting for the anesthesia to take effect takes longer. I cannot give any more details because ACTC never gave enough details in its presentations. The Japanese provide more info.
    Sep 15 02:54 PM | Likes Like |Link to Comment
  • Advanced Cell Technology Annual Meeting Announcement: A Harbinger Of...? [View article]
    Sorry, I cannot find a link that plays the video but here is a link on the 1/2 hour shows you can watch if you have over the air NHK TV broadcast in your area.

    http://bit.ly/YM8YVz

    If you go to the bottom you will find two broadcasts on iPS cells listed. The link only gives you an idea of what they showed. They don't seem to have streaming available. They offer apps ...... explore it, it may give you what you want. I do not stream so I do not know. (I have recordings of the two shows in my computer.)
    Sep 15 02:22 PM | Likes Like |Link to Comment
  • Advanced Cell Technology Annual Meeting Announcement: A Harbinger Of...? [View article]
    The greatest asset of ACTC is that its science is solid and the Trials will soon show this is so. I say this because of other information I have gathered from other sources. Here is some information from NHK World TV programs.

    Last Friday NHK News mentioned (about a 20 second clip) that the Japanese researchers are conducting a stem cell trial on AMD and have just completed one on a 70 yr old lady who, after the operation (no time specified) said she was seeing better (no detail on how much better). The cells were taken form her skin, differentiated (not mentioned), and cultured in their labs. The bad section under the retina (graphics showed a bloated blood vessel) was removed and a section of the cultured stem cells inserted in its place. The researchers are now watching to see if the cells hold. They are going to try on 5 other people (time duration not mentioned).

    Based on info from other NHK programs, this trial involves iPS cells (adult derived cells) not embryonic cells (heSC) used by ACTC. The trial is on WET AMD not DRY AMD as with ACTC trials. The Japanese researchers have been at this for many years, one of them have received a Nobel prize on his work on stem cells.

    This Japanese trial indicates the ACTC cell therapy will work and work well. It looks like there is heavy competition coming from the Japanese. I look at this as a positive because it could very well put pressure on ACTC and the FDA to get moving on the Trials and get the treatment approved.
    Sep 15 11:30 AM | Likes Like |Link to Comment
  • Update: Advanced Cell Technology Reverse Split [View article]
    Esek,

    Any opinion or comment on the SEC press release yesterday 10 Sept 2014?
    Wasn't this case settled back in Dec 2013, or is this a new one? It seems to be dragging down the share prices significantly this morning.
    Sep 11 02:56 PM | Likes Like |Link to Comment
  • ACTC: Have The Stars Finally Aligned For A Breakout Year? [View article]
    Question for the Author: With yesterday's press release that mentions that the SEC has a case against ACTC and former CEO Gary Rabin, was this not settled last Dec 2013 as you mentioned above? Or is this a new case?

    "The SEC settlement was a necessary step forward in pursuing a company objective to secure institutional funding and uplist to a more senior exchange. The company was fined $4.1 million dollars and has been permitted to pay the fine over the next six quarters. "
    Sep 11 02:39 PM | Likes Like |Link to Comment
  • ACTC completes 1:100 reverse split [View news story]
    In the 8 cents range a good Publication would have easily doubled the share price. Now that it is in the $7-8 range (yes, that is where it will be for a while), a good Pub will only kick it up to the $10-12 range.... or 25-50% rise. We longs just got screwed!
    Aug 28 08:05 AM | 1 Like Like |Link to Comment
  • Advanced Cell Technology: Maximizing Profit On Reverse Splits And Phase I Results [View article]
    If my memory serves me right shareholder authorized ratio is from 20:1 up to 100:1 R/S. The previous shareholder authorized ratio that expired last year was 80-200:1.
    Aug 27 03:53 PM | Likes Like |Link to Comment
  • Advanced Cell Technology: Maximizing Profit On Reverse Splits And Phase I Results [View article]
    In one of the CC's, ACTC pointed out that they were surprised to find that in people who have had AMD for many years, the rods and cones were just dormant, not dead as they expected. The R&C's were revived by the cell injection. I believe Smith on Stocks mentioned this in one of his articles covering that CC on SA. It would be interesting how this is discussed in the Publication.
    Aug 27 03:36 PM | Likes Like |Link to Comment
  • Advanced Cell Technology: Maximizing Profit On Reverse Splits And Phase I Results [View article]
    Around the fall quarter last year, ACT Management talked about not going through with the planned 200,000 cell cohort because the trial data they have gathered up to the 150,000 cell injections indicated it was sufficient. There was talk of asking the FDA to approve skipping the 4th cohort and thus save time. Eventually, they went through with it. I am not sure that 4th cohort trial's results will be included in the publication.
    Aug 27 03:26 PM | Likes Like |Link to Comment
  • Advanced Cell Technology: Maximizing Profit On Reverse Splits And Phase I Results [View article]
    Over a year ago, ACTC requested FDA for approval of an additional cohort, dubbed Phase 1a ( at 150,000 cells per injection ). The cohort would consists of younger people than in the those in Phase 1, and the goal was to see if they will have better efficacy. The Ph 1 cohorts of 100,000 and 150,000 cells indicated that this is likely to happen. Therefore, people's focus should be on the efficacy of Ph 1a.
    Aug 26 04:50 PM | 2 Likes Like |Link to Comment
  • Update: Advanced Cell Technology Conference Call [View article]
    Research is being conducted in Japan to treat wet AMD using iPS Cells. They are about 12 to 24 months behind ACT in their trials. There are a lot of similarities in their approach to treatment but for their use of iPS cells.
    Aug 14 11:17 PM | Likes Like |Link to Comment
  • Update: Advanced Cell Technology Conference Call [View article]
    Ph 1b Trials was requested by ACT and granted by FDA. This extra cohort trial was to treat patients who are younger than the 70-80 year olds they had treated with the 50K and 100K doses. ACT wanted to find out if the results would be more successful with the much younger patients.

    If my memory serves me right, ACT has already injected 3 patients with 150K cells and are just waiting for the end of the 6 month period.
    Aug 14 11:06 PM | Likes Like |Link to Comment
  • What Is Sirius XM Worth? [View article]
    I always enjoy reading your comments as well as SF and CN whenever an article like this appears.... especially a quality article like this.

    SIRI keeps offering programs on special occasions and this really sets them quite a ways apart from the all music competition. I would love to see SIRI offer special programs on the political arena as we approach every election, perhaps on the last 6-8 weeks prior to election day. On Presidential election years this would be easy to so since Candidates will be of National interest. This year, it will be tough to do for the interest is for local Congressmen and Senators. But inclusion of political discussions will definitely help gain many more SIRI subscribers.
    Aug 4 11:48 AM | Likes Like |Link to Comment
  • Q2 Earnings Down 4%, At 56x P/E Sirius XM Is A Short [View article]
    Watch the volume today ..... could be a good indicator of a SIRI buy back. It is a great time for SIRI to do so.
    Aug 1 12:13 PM | 3 Likes Like |Link to Comment
  • Sirius XM: You Won't Believe What I Found In The Q2 Report [View article]
    Nice clippppp. Reminds me of the good old Chipmunks performances.... on vinyl. Thanks SF.

    Oh, as you intoned in your article, I am looking forward to a great 3Q report.
    Jul 30 11:55 AM | Likes Like |Link to Comment
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