satori

Indevus Pharmaceuticals: Nebido Has Lost Its Libido

Dear usdoctor,

I am well aware of the issues you sxpeak of here as far as the long-term ineffectiveness of Testosterone replacement therapy. I have suffered from hypogonadism since my early 20s, and I have felt the effectiveness of various forms of TRT diminish within a few months of use. I wonder if a powerful aromatase injhibitor such as Arimidex can be of value in restoring a more favorable testerone- estrogen ratio -- do you have any experience with Arimidex for this purpose? Also, how much can exercise (aerobic and/or weightlifting) help to trigger more production of testosterone? Are FH and LSH levels sensitive to activity such as exercise?

Thank you in advance for your response.

S



On Jan 29 09:39 PM usdoctor wrote:

> The truth is, since I am a physician who prescribes 'T' to hypogonadal
> men is that:
> 1. gels aromatize to estrogen and will decrease bio-available testosterone
> after 6 months of use.
> 2. Testopel under Slate Pharma raised the price of the 75mg pellet
> from $12.50 to $60 each. Using 5 per month gets very expensive<br/>3.
> The 3-month Nebido does not have a flat release, but will have a
> high initial blood level that triggers the same aromatization and
> then the low levels persist for months.
>
> None work well. The best is weekly self-administered injections or
> compounded non-aromatizable testosterones. Cost $25-50 per week.
>
>
> That is the 25 year truth.