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IALF

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  • The Spare [View instapost]
    Congrats
    Jan 8, 2014. 07:19 AM | Likes Like |Link to Comment
  • NICE seeks additional information from Sanofi on Lemtrada [View news story]
    "The committee has asked the manufacturer to provide further complex and detailed evidence of the cost effectiveness of alemtuzumab compared with other disease modifying treatments."

    http://tinyurl.com/p5o...
    Dec 6, 2013. 10:10 AM | Likes Like |Link to Comment
  • Another Setback For Lexicon, But Not In Diabetes [View article]
    I'd really like to see the data they used to support their statement that adjusting for the placebo dropout, the 500mg tid was significant (p<0.05).

    I'm curious of the value before, number of drop-outs in both groups, etc.
    Dec 3, 2013. 03:04 PM | Likes Like |Link to Comment
  • Lexicon Pharmaceuticals falls on LX1033 top-line data [View news story]
    "Further analyses of the stool consistency data were performed adjusting for early terminations which may have enhanced the placebo response rate. These additional analyses of stool consistency yielded favorable results for the LX1033 500mg three times daily dose group compared to placebo, and some of these findings were associated with statistically significant results (p<0.05)."
    Dec 3, 2013. 08:29 AM | Likes Like |Link to Comment
  • With 'Progress' Like Lexicon's, Who Needs Failure? [View article]
    The data I was interested in seeing was a comparative study of LX4211 vs canagliflozin and a cardio study measuring changes from baseline in QTc intervals.

    I see these more important in the short run as compared to T1D as it could deter from a P3 in T2D.

    LX4211 vs canagliflozin to show if it is better than what is currently marketed. If not, I see less foothold for it.
    Cardio to show if the drug changes QTc, as this is a safety concern for T2D drugs. If does cause these changes then I personally would pass for another drug.
    Nov 13, 2013. 11:12 AM | Likes Like |Link to Comment
  • With 'Progress' Like Lexicon's, Who Needs Failure? [View article]
    I'm with you there Stephen, I wish there was a little more definitive of a response when it comes to partnership and advancement of LX4211.

    I was hoping to hear about a few studies in LX4211 that clinicaltrial.gov shows as recently completed, but there was no mention of any of the three studies. I keep thinking to myself 'this study has to be the final key', but still sit waiting.
    Nov 13, 2013. 10:29 AM | 1 Like Like |Link to Comment
  • Chart Of The Day – Wednesday, October 30, 2013 [View instapost]
    I noticed a slight difference when I went from west Michigan to north Ohio. Growing season was just different enough to throw my plans - first year I lost a little growing season.

    I'll be saving this chart as well, first time I grow a new plant I'm always confused as to the best start date.
    Oct 30, 2013. 10:53 AM | Likes Like |Link to Comment
  • Chart Of The Day – Wednesday, October 30, 2013 [View instapost]
    Is that general or for Maine?
    Oct 30, 2013. 10:40 AM | 1 Like Like |Link to Comment
  • Humor – Monday, October 28, 2013 [View instapost]
    Still one of my favorite webcomics.
    Oct 28, 2013. 09:43 AM | 1 Like Like |Link to Comment
  • Humor – Tuesday, October 08, 2013 [View instapost]
    Story of my life.
    Oct 8, 2013. 02:34 PM | Likes Like |Link to Comment
  • Will More Good Data From Lexicon Finally Bring In A Partner? [View article]
    I'm still in love with this company. Showing effectiveness in patients with renal failure is huge as this combination reduces the number of medications one can take making any such medication more important.
    Here's to hoping this was the final piece in the partner puzzle.
    Oct 2, 2013. 02:07 PM | 1 Like Like |Link to Comment
  • Rangeley Fall Foliage II [View instapost]
    We should put a hold on winter, I'm enjoying fall.
    Oct 1, 2013. 11:20 AM | 1 Like Like |Link to Comment
  • Wall Street Breakfast: Must-Know News [View article]
    I feel bad for the workers, but how much can you expect to make doing something that practically anyone can do?

    Learn a trade...
    Aug 30, 2013. 08:26 AM | 13 Likes Like |Link to Comment
  • Expensive S*** [View instapost]
    I believe Chris is right, if you sign up you can use the promo code for the first sale. The scheduled rate discount should continue if you wish to continue shipments.

    If you do not, you can cancel the Amazon Prime account after a shipment.
    Aug 28, 2013. 08:25 PM | 1 Like Like |Link to Comment
  • Rexahn's Oncology Platform Led By Its Akt-1 Inhibitor Challenges Big Pharma With Ground-Breaking Cancer Therapy [View article]
    in vivo refers to testing in living organisms, e.g. animal testing, human testing

    in vitro refers to testing in cells, e.g. test tubes, plates
    Jun 5, 2013. 08:45 AM | 2 Likes Like |Link to Comment
COMMENTS STATS
29 Comments
66 Likes