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Anybody try digital tradz ?
Nov 14, 2009. 09:26 PM
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Mannkind: Overlooked Biotech With Excellent Prospects (Part III)
Then why are institutions selling heavy this year? Seems that they would be able to do much more research then you and make a better judgement.
On 2008 Jun 13 04:43 AM R.J Steffens wrote:
> "This was yet another obstacle to prescribing Exubera, especially
> since most doctors treating diabetics (i.e. general practitioners
> and internists) do not have pulmonary testing equipment in their
> offices. On the other hand, Mannkind found no evidence of any drop
> in lung function whatsoever in their clinical trials with Technosphere
> Mannkind has not reported detailed Phase III results, and did not
> report the additional safety data at the ADA event like they stated
> they planned on doing. The did have ana abstract showing absorbtion
> occuring 8 minutes later for smokers then for non-smokers as measured
> by "tmax". The FDA, in my opnion, would require a diabetic to undergo
> pulmonary tests for technosphere (if it is ever approved). The diabetic
> already is losing lung function due to the progression of the desease:
> "(5) Chronic use of inhaled insulin may affect long-term pulmonary
> function, while preexisting pulmonary dysfunction may alter the absorption
> and bioavailability of inhaled insulin."
> Another worth mentioning is Generex's Oral-lyn Buccal spray. Since
> Oral-lyn also has a very rapid onset of action, and NO deposition
> into the lungs, it seems as if it would be the choice amongst diabetics
> between these two potential products. Technosphere is said to afford
> low titration and Oral-lyn provides 1 U sprays as part of a fine
> tune regimen. Technosphere has another large obstacle that Oral-lyn
> does not- TI needs to be marketed as a product that does not cause
> decreased lung function or lung cancer. Fair or not, that is a horrible
> position to be in. I wish them well, and hope they all are approved
> to give diabetics a new choice and lifestyle freedom. This is a freedom
> they have in India with Oral-lyn.
> Best wishes.
Nov 4, 2009. 09:04 PM
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