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SMaturin

SMaturin
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  • Axion Power Concentrator 282: Nov. 10 '13: Axion & Norfolk Southern At ASME Rail Conference; John Petersen Joins EPower [View instapost]
    Please don't mock my dark chocolate collection!

    It has taken me years of travel to many distant places.

    Some of them are mounted on the living room wall.

    How would I explain their absence to SWMBO?
    Nov 11 08:17 PM | 5 Likes Like |Link to Comment
  • Stability Of The European Union (22) November 9, 2013 To December 31, 2013. [View instapost]
    How is this different from our Social Security Trust Fund?
    Nov 11 06:33 PM | 2 Likes Like |Link to Comment
  • QuickChat #264, October 24, 2013 [View instapost]
    I don't think the Fed is hiding it so much assuming the general public is too math-challenged to understand the reality.

    Like TB, I think one needs to assume that "If you cannot dazzle them with brilliance, then baffle them with Bü!!$#!+" is the name of the game at the Fed.
    Nov 11 06:23 PM | 5 Likes Like |Link to Comment
  • Swine Flu AND Medical News Concentrator November 9, 2013 To December 31, 2013. [View instapost]
    Yes, ouch.

    The Z160 phase 2 bombed today. I am left holdinng the bag and hoping Z944 pans out. I may just have to take my losses on that one.
    Nov 11 06:13 PM | 2 Likes Like |Link to Comment
  • Axion Power Concentrator 282: Nov. 10 '13: Axion & Norfolk Southern At ASME Rail Conference; John Petersen Joins EPower [View instapost]
    I just discovered a use of Li Ion transport technology I can actually covet. Check out the new line from caterham bikes, with the Carbon E-Bike.

    http://caterhambikes.com

    What I am really drooling over is that Brutus dual sport motorcycle. But my SWMBO would do twice to me what VW's did to him if I suggested I "need" a $25 toy to conserve fuel commuting to work.
    Nov 11 01:16 PM | 6 Likes Like |Link to Comment
  • Axion Power Concentrator 282: Nov. 10 '13: Axion & Norfolk Southern At ASME Rail Conference; John Petersen Joins EPower [View instapost]
    Look on the bright side, VW.

    Now there is no possibility that her Herness will ever be able to read it and make you do all those unbearable things!
    Nov 11 08:27 AM | 7 Likes Like |Link to Comment
  • Stability Of The European Union (22) November 9, 2013 To December 31, 2013. [View instapost]
    If only Congress could be defined by both terms. Non-human, it fits. Intelligence, well...

    "Suppose you were an idiot and suppose you were a member of Congress; but I repeat myself." -Mark Twain
    Nov 10 06:00 PM | 4 Likes Like |Link to Comment
  • Axion Power Concentrator 281: Nov. 07 '13: Axion & Norfolk Southern At ASME Rail Conference; John Petersen Joins EPower [View instapost]
    VW,

    If her Herness ever reads this, you will have to do all of the above.
    Nov 9 04:31 PM | 8 Likes Like |Link to Comment
  • Swine Flu AND Medical News Concentrator November 9, 2013 To December 31, 2013. [View instapost]
    Maya, (ARNA) peaked around 12 back in late June 2012 (with a 13.50 spike) just after the announcement of FDA approval of Belviq (lorcaserine). I had been buying since the previous March at 1.77, because I became convinced they had met the expectations of the FDA's complete response letter even before the ADCOM in May 2012 said it looked good.

    I cashed half my position at 7.50 the week before approval, and have been letting the other half ride. It has been painful watching it tumble over the past year and a half, as they were very slow to get it finally on market, and had to wait for the bureaucratic gears to grind out a DEA scheduling decision.

    But I have faith that this drug will do well worldwide, and ARNA looks like an amazing bargain at the recent prices under $5, if you are looking to buy and hold long-term.

    If I had the powder, I would be buying more on this recent news.
    Nov 9 03:37 PM | 2 Likes Like |Link to Comment
  • Axion Power Concentrator 281: Nov. 07 '13: Axion & Norfolk Southern At ASME Rail Conference; John Petersen Joins EPower [View instapost]
    Sleek.

    Nissan BladeGlider.

    http://bit.ly/HOTtmh

    I want one with Axion Inside.
    Nov 9 03:23 PM | 5 Likes Like |Link to Comment
  • Axion Power Concentrator 281: Nov. 07 '13: Axion & Norfolk Southern At ASME Rail Conference; John Petersen Joins EPower [View instapost]
    "We could tell you the recipe, but then we'd have to kill you."
    Nov 9 12:15 PM | 8 Likes Like |Link to Comment
  • Stability Of The European Union (22) November 9, 2013 To December 31, 2013. [View instapost]
    What an excellent analogy: "an Escher economy."

    "We're Stuck In An Escher Economy Until The Existing Structure Collapses And Is Rebuilt On Stronger Principles"

    http://bit.ly/HNb2nN
    Nov 9 12:00 PM | 3 Likes Like |Link to Comment
  • Stability Of The European Union (22) November 9, 2013 To December 31, 2013. [View instapost]
    Ditto, HTL and WT.

    But I would use the word "variegated" instead of "untainted." I like to get views from alternative perspectives, but I assume that none of them are truly unbiased or untainted. Our human nature precludes pure objectivity.

    Maybe someday when SkyNet takes over we can have a non-human intelligence that can simulate pure objectivity.
    Nov 9 11:44 AM | 5 Likes Like |Link to Comment
  • Swine Flu AND Medical News Concentrator November 9, 2013 To December 31, 2013. [View instapost]
    Thanks, Ratso.

    I just posted a comment over on Larry Smith's recent article about (NBY) to expand on my thinking about auriclosene applications.

    http://seekingalpha.co...
    Nov 9 09:20 AM | 3 Likes Like |Link to Comment
  • NovaBay: Phase II Topline Results For Auriclosene In UCBE Are Very Encouraging (NovaBay, $1.57) [View article]
    Larry, my expectations were the opposite. Auriclosene is essentially a topical contact disinfectant, rather than an antibiotic. Empetigo is an infection of skin tissues that goes deeper than topical disinfectants may penetrate. Standard oral antibiotics can achieve microbicidal tissue concentrations where a topical agent cannot, so I thought the empetigo application did not make a lot of sense to me, as a water-soluble ionic disinfectant (auriclosene) may not penetrate the epidermis very effectiviely.

    On the other hand, the conjunctivitis application makes more sense. The conjunctiva is a mucous membrane environment where a water soluble agent will readily penetrate the surface layers and do its antiseptic thing.

    Similarly, urinary catheter encrustation is the ideal application for auriclosene, because it is in that aqueous environment of the bladder that Proteus mirabilis biofilms on the catheter split urea to create ammonia and an alkaline solution, causing precipitates of calcium and urate crystals in the biofilm, which accumulates until it blocks the catheter. Oral antibiotics do not easily penetrate the biofilm to stop that process. Auriclosene does, without harming the surrounding bladder mucosa. There are no other really effective solutions for catheter flushes on the market that are both this safe and this effective at killing P. mirabilis.

    The UCE application has far more potential in my mind for a stable large market for auriclosene, as patients with indwelling catheters will need weekly applications essentially for life, to reduce the morbidity and cost associated with blocked catheters, bladder infections, and frequent replacements of catheters.

    This price plunge on the news about empetigo P2 study reflects a profound misunderstanding by the market of how exactly auriclosene works as a unique new agent. It is not an antibiotic, and treating existing infections will not be its strong point. It is a novel, bio-derived antiseptic, which will be very useful for wound and catheter and surgical antisepsis management. That is the market NovaBay should be targeting.

    My $0.02 as a physician.
    Nov 9 09:09 AM | 5 Likes Like |Link to Comment
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