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Trovagene: An Interesting Precision Medicine Developer

|About: TrovaGene, Inc. (TROV)
Summary

Various elements are required for a successful bioscience investment.

Stellar assets are one of the key requisites. However, the molecule in development still needs strong patent protection.

Strong cash position is another requirement because it takes tremendous capital to fund a molecule from bench research to commercialization.

Trovagene is leveraging on combination therapy and precision medicines to innovate a novel drug, onvansertib for the management of many cancers.

We present an analysis of the promising prospects of Trovagene and the extremely high risks associated with this investment.

The stock investor is neither right or wrong because others agreed or disagreed with him; he is right because his facts and analysis are right. - Benjamin Graham

The bioscience sector presents many promising investment prospects, especially in this bear market. Therefore, we’re continuously on the hunting for truly bargain growth companies. Nonetheless, it is important for investors to perform extensive due diligence on a potential investment from multiple lenses. The more perspectives one can assess a company, the better the investment accuracy and the higher the profits. For instance, some companies have excellent technology. And yet, it does not have strong patent protection. Other companies have stellar technology and strong intellectual property protection but it might not have adequate capital to fund further pipeline innovation. In this research, we’ll present a fundamental analysis of a highly promising company, Trovagene (NASDAQ:TROV) and what investors can expect from this interesting innovator.

Figure 1: Trovagene stock chart (Source: StockCharts)

About The Company

Based in San Diego California, Trovagene is a bioscience innovator that is riding on the wave of precision medicine to develop stellar cancer therapeutics. As shown in Figure 2, the company is advancing onvansertib to potentially manage various blood cancers as well as solid tumors. Back in March 2017, Trovagene licensed the global right to onvansertib from the Italian research and development company, Nerviano Medical Sciences. As a Polo-like Kinase (PLK1) Inhibitor, onvansertib is a first-in-class, 3rd generation, orally available, and highly-selective adenosine triphosphate (“ATP”) competitive inhibitor of the serine/threonine polo-like Kinase (PLK1) enzyme. Since PLK1 is found on many cancer cells, suppressing PLK1 can be an excellent approach to the management of various cancers.

Figure 2: Therapeutic pipeline (Source: Trovagene)

PLK1 Inhibition As A New Approach To Manage Cancer

A cornerstone of cancer treatment is the suppression of cellular division (i.e. mitosis) to eradicate cancer cells because they divide rapidly. As PLK1 is involved in regulating cellular division and maintaining genome stability in mitosis, the inhibition of PLK1 can halt the cell cycle and thus leads to cancer cell death (i.e. apoptosis).

Final Remarks

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Disclosure: I/we have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours.