PR NewswireMarch 2, 2017
SAN DIEGO, March 2, 2017 /PRNewswire/ --
CheckPoint Formed as a Subsidiary of the Company to Simplify any Potential Future Transactions Involving the Company's NR2F6 Technology
Regen BioPharma Inc. (RGBP), (RGBPP) has granted CheckPoint Immunology Inc. (a wholly-owned subsidiary of the Company) an exclusive worldwide license to develop and commercialize Regen's NR2F6 technology for human therapeutic use. The objective of the license grant is the separation of Regen's small molecule technology from its other intellectual property in order to facilitate any future transactions involving small molecule therapies focused on the NR2F6 checkpoint.
The Company's focus on NR2F6 has two developmental streams. The first area of development involves the inhibition of the checkpoint, NR2F6, in order to cause the body's immune system to destroy cancer cells. The second area of development involves the activation of NR2F6 which is believed to be a fulcrum for curing such autoimmune diseases as rheumatoid arthritis.
Regen BioPharma's Chairman and CEO, David Koos, stated, "In the beginning, Regen's business model was created with the goal of developing intellectual property to a point of attracting large pharmaceutical companies, to participate in maturing Company assets, either by sale, license or co-development. By forming CheckPoint Immunology, we are setting our game plan in place so that as we get further along in our development of small molecule therapies for treating cancer and autoimmune diseases, we can structure a transaction specific to NR2F6-related therapies. The Company has been approached by numerous parties interested in our NR2F6 based therapies. We expect, as we further optimize our small molecule compounds, there should be even greater interest. Hence the reason for creating CheckPoint Immunology is as a pure vehicle for any future NR2F6 transaction."
Dr. Harry Lander, Regen's president and CSO, noted, "Biotechnology companies focused on successful immune-oncology therapies are generally granted trophy value transactions (e.g., deals that have a value in excess of $1 billion). In addition to our intent to create a first-in-class immune checkpoint inhibitor for treating cancers, we also plan to exploit the anti-autoimmune aspects of our small molecules as well. Thus, while we can't anticipate what our valuation will be if our programs pan out, it's good to know we're swimming in the right pool."
Currently CheckPoint Immunology is at the lead optimization phase of its medicinal chemistry program. The Company anticipates that once results of the medicinal chemistry program being conducted by ChemDiv, Inc. are available, we should be in a position to form alliances with large companies interested in NR2F6 inhibition for cancer therapy or NR2F6 activation for treating autoimmune disorders.
Previous Items of Significance
HemaXellerate's approval and clearance by the FDA to commence Human Trials with the New Drug. That resulted in two things. One RGBP transitioned from a R&D company, morphing into a Clinical Trials Company, a major step in the progress of the company and credibility. Second RGBP attracted their first viable partner as the (NIH) agency NCATS agreed to collaborate with clinical trials using HemaXellerate for a treatment of the rare blood disease/disorder aPlastic Anemia.
New Partners - NIH (NCATS) - Pan Am Cancer Research and Treatment Center - Eli Lily & Company -
Weill Cornell Medical College (Cornell University)
HemaXellerate II was discovered to be effective in treating an additional market much more vast than aPlastic Anemia. It is in the early stage of development to treat Bone Marrow Suppression, a common disorder due to Chemotherapy. This finding occurred at/with another new partner The Pan Am Cancer Research and Treatment Center where ongoing Trials are being conducted.
Regen BioPharma Submits Application to FDA for Orphan Drug Designation for its HemaXellerate Product
dCell Vax (Treatment for Breast Cancer) seems to be at last news in the final comments with the FDA to gain approval to commence Human Trials with Breast Cancer Patients.
The NIH (NCATS) also is collaborating with Regen and working together to screen small molecule compounds that activate or inhibit orphan nuclear receptor, NR2F6 (Research Project), cell lines will be provided by Regen. Regen also has a partnership with Eli Lily working together with NR2F6.
For all the news-Details on other treatments HemaXellerate I, HemaXellerate II, dCell Vax, NR2F6, Tcellvax, uCell Vax, Car-T Cell for various Cancers, Autoimmune, Rare Blood Disorders/Diseases, Leukemia, etc. Open the link below.
We believe Regen BioPharma is a Long Play, with a great upside with all the items in its Pipeline. Very possibly a Buy Out Target-They do already have some impressive Partners, today that list Grew.
RGBP also has Short Term Gain Potential that has been proven time and again since we began following them. Most recently with a 60% move up, until a slight dip, yet still up about 40% since 2/21/17. Increases-Bounces in Share Pricing ranging from 30%-400% do occur.
Take a Look at this Diamond in the Rough. Profit more than likely awaits at this entry level.
Robert E. Kreh
Small Cap Solutions, LLC
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