shcri.com - New technology has evolved to tackle degenerative spinal disease, but is enough post-surgery data available to make claims on the efficacy of vertebral implants, asks Cervical Total Disc Replacement - Global Analysis and Market Forecasts.
Symptomatic Cervical Disc Disease (SCDD) is a degenerative condition of the spine that can cause debilitating pain and neurological dysfunction. Around 11 million individuals across the globe reportedly suffered from SCDD in 2011, and this number is set to grow as the global population ages. - Cervical Total Disc Replacement - Global Analysis and Market Forecasts
For several decades, Anterior Cervical Discectomy and Fusion (ACDF) represented the hallmark surgical intervention for SCDD, alleviating pain by removing the affected intervertebral disc and fusing adjacent vertebrae together. However, years after the commencement of these procedures, many individuals post-operatively developed SCDD in intervertebral disc levels adjacent to those which were operated on. It is thought that the fusing of adjacent vertebrae may have prompted the progression of SCDD along the spine. Cervical Total Disc Replacements (C-TDR) were thus invented to alleviate pain by replacing the damaged disc completely, retaining the motion of the operated level. - Cervical Total Disc Replacement - Global Analysis and Market Forecasts
The C-TDR marketplace is still relatively new, and evidence has been established of the device's safety and efficacy performance, with two to five year follow ups having been produced. However, there remain several clinically unexplored avenues in the C-TDR market. - Cervical Total Disc Replacement - Global Analysis and Market Forecasts
Heterotopic ossification - the formation of bone outside of the skeleton - has become a growing concern for C-TDR patients, as an increasing prevalence has been documented years after procedures are performed. The durability and longevity of the devices has also raised questions, since they are intended for permanent implantation. In addition, there is a lack of clinical investigation into the performance of C-TDR devices in the over 65 year old patient population. There has been some surgeon hesitance on treating this group with these devices largely because of recommendations produced in literature for lumbar disc replacements. There is also a lack of large-scale trials assessing the performance of C-TDR against ACDF in double level procedures. - Cervical Total Disc Replacement - Global Analysis and Market Forecasts
"The C-TDR market is becoming increasingly competitive with players routinely obtaining non-inferiority performance to ACDF" says Cervical Total Disc Replacement - Global Analysis and Market Forecasts "Companies can leverage these clinically unmet needs to further differentiate themselves".
The cost effectiveness of these devices over ACDF procedures in the long term is also yet to be explored, and positive results will prove vital to improved reimbursement coverage.
Cervical Total Disc Replacement - Global Analysis and Market Forecasts estimate the 2018 C-TDR sales to reach over US$756m across the US, France, Germany, Italy, Spain, the UK, Brazil, India, and China. Future market growth will be primarily fueled by increased adoption in the United States and the Asia Pacific region.
This report provides comprehensive analysis on the current and future performances of nine major Symptomatic Cervical Disc Disease (SCDD) markets, in Brazil, China, France, Germany, India, Italy, Spain, the US, and the UK. It also provides actionable insights for existing or future competitors, identifying unmet needs and opportunities.