No evidence of increased risk of development, metastasis or recurrence of breast cancer in contrast to laboratory data says published clinical experience in over 2,000 patients who received autologous fat grafts.
- This includes procedures in which the graft has been enriched with adipose-derived stem and regenerative cells (ADRCs).
A newly published review entitled “Oncologic Risks of Autologous Fat Grafting to the Breast” in the January issue of the American Society of Aesthetic Plastic Surgery’s Aesthetic Surgery Journal discusses the data disparity between the clinical and certain laboratory-based scientific literature regarding fat grafting procedures to the breast.
- The article, authored by John Fraser, Ph.D. and Marc Hedrick, M.D. of Cytori Therapeutics and Steve Cohen, MD evaluates the theoretical concerns raised by fat grafting procedures to the breast (particularly in women who have undergone treatment for breast cancer);
- This analysis is consistent with Cytori preclinical studies, demonstrating that cell-enriched fat grafting did not increase the risk of breast cancer development or metastasis and in some situations, actually decreased cancer growth.
The article explores potential issues and concludes that the apparent data discrepancy between the laboratory and the clinic are the result of the application of artificial conditions used in certain laboratory studies that do not arise in a clinical setting.
- The January issue of the Aesthetic Surgery Journal is online at http://aes.sagepub.com/content/current.