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power3 Power3 Medical Products Inc. (OTC:PWRM)

Power3 Medical Products, Inc. is a leading bio-technology company focused on the development of innovative diagnostic tests in the fields of cancer and neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (commonly known as ALS or Lou Gehrig's disease). Power3 Medical applies proprietary methodologies to discover and identify protein biomarkers associated with diseases. Through these processes, Power3 Medical has developed a portfolio of products including BC-SeraPro™, a proteomic blood serum test for the early detection of breast cancer for which it has completed Phase I clinical trials, and NuroPro®, a proteomic blood serum test for the detection of neurodegenerative diseases, including Alzheimer's, Parkinson's, and ALS diseases, for which it is currently engaged in Phase II clinical trials. These tests are designed to analyze an individual's proteins to detect the presence of disease, a patient's disease progression, a patient's response to a particular drug, and the mechanisms of disease present in the patient for optimal targeted therapy.

There are two types of Alzheimer's disease, early-onset and late-onset. Early onset occurs before the age of 60-65 and is thought to be linked to genes on certain chromosomes. Mutations in these genes affect a protein called beta-amyloid , which causes damage in the brain when it builds up. Only a small percentage of Alzheimer's disease is early onset and because it is linked to genes, it can run in families. As a result, early onset is often referred to as familial Alzheimer's disease.

Early onset of Alzheimer's disease is also common in people with Down's syndrome. Down's syndrome is a result of having three copies of chromosome 21 instead of the regular two. It has been found that chromosome 21 can cause an excess of beta-amyloid to be produced. Having an extra chromosome 21 therefore produces even more beta-amyloid plaques.

The more common form of Alzheimer's disease is known as late onset. This type affects those over the age of 65 and appears to be related to a mutation on a gene known as ApoE.

The NuroPro Blood Test of Power3 Medical Products, Inc is a diagnostic tool for the early detection of Neurodegenerative diseases. The analysis is designed as a tool for physicians to diagnose various degenerative diseases of the brain and nervous system. The test involves monitoring the concentration of 59 proteins in blood serum to accurately detect and distinguish between Alzheimer's disease, ALS (Lou Gehrig's disease), and Parkinson's disease. Early detection of these diseases would allow physicians to intervene at an early stage to delay disease progression, potentially allowing patients to outlive their debilitating symptoms.

For more information about Power3 Medical Products, Inc., please visit http://www.power3medical.com

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http://bestotc.com/img/orfgx.png Orofino Gold Corp. (ORFG)

Orofino Gold Corp. President Ary Pernett and Vice President of Development Alfonso Calderon of Orofino Gold Corp. (ORFG) hosted investors interested in a firsthand look at the company's Senderos de Oro projects. These visits come as investors consider the financial commitments necessary to fund exploration and provide modern mining techniques and equipment to the area.

The group spent four days in Colombia during which they had an opportunity to tour Orofino's active mine sites at La Azul, Culo Alzado, and Buena Sena. The visit offered investors an opportunity to observe current artisanal gold production, and an in-person view of Colombia's revitalized foreign investment opportunities and stability. Following this site visit, Orofino's directors and investors are expected to prepare for the company's future funding and development needs as it continues to expand exploration at Senderos de Oro.

Orofino Gold Corp. has several Gold development properties in Colombia, a current hot spot of gold production in the world markets. Orofino Gold Corp. is a Colombia based gold producer founded as a private company in 2009 by former executives with over 50 cumulative years in mining exploration, finance, and development expertise. Orofino's corporate objective is to continue to build shareholder value through the exploration and development of Senderos de Oro and additional accretive acquisitions, capitalizing on the extensive experience and relationships that management has developed over the past 25 years.

Gold is represented by the symbol 'Au'. Gold is heavy and dense. Gold is inert in nature. It is neither corroded by air nor affected by most of the reagents. Gold is one of the precious metals coveted by man. With a few exceptions, almost all men and women dream of possessing gold. In one or another form, it has attracted admirers through all ages and civilizations.

La Azul (formerly La Estrella) is an artisanal gold production mine in the Senderos de Oro area controlled by Orofino. La Azul is composed of a mixed sequence of predominantly volcanic rocks featuring vein systems comprised of high grade chalcopyrite, galena and sphalerite with pyrite in quartz viens.

For more information about Orofino Gold Corp. visit its website
www.orofinogoldcorp.com

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Pepsico, Inc. (NYSE:PEP) announced at the Beverage Digest Wall Street Smarts conference that the company will test, beginning in July, a new reduced-sugar cola, Pepsi NEXT, in two markets in Iowa and Wisconsin. Pepsi NEXT leverages both the formulation expertise of PepsiCo's R&D team, which delivered this great-tasting, new cola product, and Pepsi's deep understanding of the evolving preferences of U.S. consumers.

PepsiCo, Inc. manufactures, markets, and sells various foods, snacks, and carbonated and non-carbonated beverages worldwide. The company was founded in 1898 and is headquartered in Purchase, New York.

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CVS Caremark Corporation (NYSE:CVS) announced that Dave Denton, executive vice president and chief financial officer of CVS Caremark, will be making a presentation to investors at the Jeffries 2011 Global Consumer Conference on June 22, 2011. Mr. Denton is scheduled to present at 10:40 AM EDT.

CVS Caremark is the largest pharmacy health care provider in the United States. Through our integrated offerings across the entire spectrum of pharmacy care, we are uniquely positioned to provide greater access to engage plan members in behaviors that improve their health, and to lower overall health care costs for health plans, plan sponsors and their members.

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Progressive Corp. (NYSE:PGR) announced that it will host a simultaneous webcast of its 2011 Investor Relations Meeting on Friday, June 17, 2011, beginning at 9:00 a.m. eastern time. The meeting will last approximately three hours and will include a question and answer session following the presentations. The meeting will also be available simultaneously, in a listen-only format, by phone. Participants via the phone will not be able to submit questions during the question and answer session. A replay of the webcast will be available on the business day following the event and can be accessed from our website at http://investors.progressive.com/events.aspx. The archived webcast will remain available until June 18, 2012. A replay via the phone will not be made available.

The Progressive Group of Insurance Companies makes it easy to understand, buy, and use auto insurance. Progressive offers choices so consumers can reach us whenever, wherever, and however it's most convenient for them-online at
http://www.progressive.com

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