Adaptimmune teams up with Alpine to develop next-gen cell therapies

|About: Adaptimmune Therapeuti... (ADAP)|By:, SA News Editor

Adaptimmune (ADAP +3.7%) will collaborate with Alpine Immune Sciences (ALPN +4.4%) to develop next-generation SPEAR T-cell products based on the latter's secreted and transmembrane immunomodulatory protein (SIP and TIP) technology.

A clinical trial evaluating the first candidate, ADP-A2M4CD8, should launch in H2.

Under the terms of the partnership, ADAP will pay ALPN an undisclosed upfront amount, research funding, up to $288M in milestones and low single-digit royalties on net sales. ADAP has the option to acquire a global license for each program.

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