Testing of Gilead's remdesivir in coronavirus patients to start tomorrow in China

• China's state-run Xinhua News Agency reports that healthcare providers at Wuhan's Jinyintan Hospital will begin treating the first group of severe coronavirus cases with Gilead Sciences' (GILD -2.2%) remdesivir tomorrow. A total of 761 patients will receive therapy.
• Chinese authorities have OK'd the start of clinical trials.

Comments

[F_BIO]

Really important news about remdesivir: www.pnas.org/...
@Matt-Man @CaptainSolo

[namkaps]

Are there initial results ?

[Matt-Man]

@namkaps Not really, just some additional details on how treatment test is being conducted:
www.chinadaily.com.cn/...

[CaptainSolo]

New York Times "If the drug works, will Gilead be able to provide enough for everyone who needs it?" www.nytimes.com/...

Gilead already has patents for the drug in China and other parts of the world, and in 2016 filed additional patent applications to use it against coronaviruses. But the company’s application for coronavirus use is still pending, Mr. McKeel said.

[CaptainSolo]

Gild stock new 12 month high. Nothing but higher all day today.
Target price $90 a share in two months.

Patent application in China since 2016.

New, news, news,

[Michael Robinson9303]

Somebody is making a big bet that this drug will be successful at treating this virus. Over 30k of the April 80 calls have been bought at close to triple what their value was at the beginning of the week.

Its still very early, but initial trials are suggesting that two older drugs, Kaletra and Nalfinivir, might be more promising treatments

[cheesepep]

Hope I can shed some insight on the patent that the Chinese company/university is doing. Gilead indeed is the inventor (or assigned the patent) of the drug -- call it X. The Chinese company is not pretending to have invented X, but rather a method of using X to prevent/treat this coronavirus. This method patent is not a patent but a patent application, as it is not been issued yet after a thorough search for prior art is found. This can take 1-3 years usually.

[Michael Bryant]

1-3 years is too long. Even SARS was contained in 8 months.

[Jozeff Agaton]

I went long in this bad boy and expiring this week. Let's go and have a successful treatment.

[SpoiledRottenBrat]

Baby tests positive for coronavirus just 30 hours after birth

www.cbsnews.com/...

[Elliott C]

Do we know what Gilead will charge per dose if & when the treatment is effective?

[Matt-Man]

@Elliott C No, but it is not relevant either. If remdesivir is effective and eventually approved for wider use, it would be stockpiled by various governments waiting for next corona virus epidemic.

Tamiflu earned $18b for similar purposes. Btw, Tamiflu was also developed by Gilead while sold by Roche now.

[biotech_gal]

If you’re taking about avian influenza I read it was more like $3b

[alpha11915]

Hope this drug works. The Chinese people have suffered a lot already. Sending everyone affected by this virus my best wishes to get better soon.

[CaptainSolo]

China lab seeks patent on use of Gilead's coronavirus treatment

www.reuters.com/...

“Even if the Wuhan Institute’s application gets authorized, the role is very limited because Gilead still owns the fundamental patent of the drug,” said Zhao Youbin, a Shanghai-based intellectual property counsel at Purplevine IP Service Co.

“Any exploitation of the patent must seek approval from Gilead.”

[smoothdf]

I read the article before, but when I saw your post I thought it said "exploitation of the patient"

[tynb95747]

What I’m saying is why chinese claim the patent in China for Gilead made not yet FDA approved drug? Chinese didn’t invent the drug Gilead did. This is so ugly and evil. Don’t be naive and get robbed.

[Forensic Investor]

Hopeful it works. Good luck!

[dabesdiabetic]

And to think Thursday was doomsday.

[rhythmbreakdown2]

Well, can it be mass produced? The chi-coms are deceptive about the real amount of the plague they created and we are helping them to save our skins. WOW

[Matt-Man]

@rhythmbreakdown2 Yes, Gilead is producing already even though effectiveness is not yet know, just in case. With patient in Seattle it showed results after just one day, hope it continues similar behavior in China testing

[newbienik]

What an idiot 'created plague' - are you serious? Sad that you even got likes from all the white supremacists

[newbienik]

Why does it take the medical community so long to start these things?

[Processchemist]

to prevent idiots from suing

[valrisk]

Gilead has a possible coronavirus vaccine. China has over a billion people and the stock is down? Is China planning on stealing the value of the patent?

[kenberthiaume]

not a vaccine, i don't think.

[valrisk]

antiviral agent not vaccine

[SelmaPete]

For the lucky few, that get the treatment, congrats. For the test of the crew, hang tough, the cavalry is coming. They are in my thoughts and prayers.
GLTU
Thanks O'Day and crew, great job!
Life is grand, enjoy

[Michael Bryant]

Is this the rumor that a university in China found two drug candidates that successfully treated coronavirus? $GILD is also down a lot over the last two years, has a 3.9% dividend yield, and has a dividend growth rate of 11%. It is a good buy.

[Matt-Man]

No, in University they did in vitro testing:"Preliminary tests showed that two drugs - Abidol and Darunavir – can effectively inhibit the virus in vitro cell experiments, according to Li, who is also a professor at Zhejiang University. "

in vitro testing is totally different than testing with actual patient. Sure above HIV drugs may also be effective, also remdesivir has been effective in vitro against various corona viruses as well as in animal testing. Real testing needs to be done with real patients

[tynb95747]

Anyone know Chinese Wuhan lab is already registered Gilead patent in China back in January? See how America intellectual property been stolen like this? Does Gilead know? Go do some research and understand who you are dealing with the evils...

[irregularpanda]

yeah....in America this drug hasn't passed basic phase 1 safety yet. It would be a pain in the butt to expedite phase 1 studies in the US, let alone phase 2, and 3, and 4 all while racing against a virus whose outbreak will possibly stop spreading at some point in the next 1-2 months. Gilead knows exactly what they're doing. They get to experiment with their drug, without passing phase 1 or 2 trials, and without fear of being sued for medical malpractice. If they get a windfall from this in treating this Corona virus, then bonus.

[Matt-Man]

@irregularpanda remdesivir is in phase 2. Has been tested with humans against Ebola as well, not as successful as competition with Ebola, though

[eenmakkie]

Can they pass the fase 2 , &4 faster ?
How long normally for all those phases?

[Matt-Man]

Significant sample size, should tell how effective remdesivir is against this corona virus.