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Mid-stage data on Allakos' lirentelimab published in New England Journal of Medicine

Oct. 22, 2020 1:02 PM ETAllakos Inc. (ALLK) StockALLKBy: Vandana Singh, SA News Editor
  • Allakos (ALLK +7.9%) has announced the publication of results from Phase 2 study of lirentelimab (AK002) in patients with eosinophilic gastritis and/or eosinophilic duodenitis in the New England Journal of Medicine.
  • All AK002 dose arms showed clinically meaningful and statistically significant benefits compared to placebo on all prespecified primary and secondary endpoints, including gastrointestinal tissue eosinophil counts and patient-reported disease symptoms.
  • Last year, the company announced positive top line data from the study, demonstrating a 95% reduction in the number of eosinophils (a type of white blood cell associated with inflammation/infection) in gastrointestinal tissue compared to a 10% increase in the control group (p<0.0001). All secondary endpoints were also met.

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