Alvotech starts confirmatory study for its AVT06 biosimilar to Regeneron's Eylea

Jul. 07, 2022 9:00 AM ETAlvotech (ALVO)REGNBy: Anuron Mitra, SA News Editor

Extreme close up eye and eyelashes

Jonathan Knowles

  • Icelandic biotech Alvotech (NASDAQ:ALVO) on Thursday said it had started a confirmatory clinical trial for its AVT06 biosimilar candidate to Regeneron's (REGN) blockbuster eye injection Eylea.
  • The objective of the study is to compare AVT06 and Eylea in terms of efficacy, safety, and immunogenicity in adult patients with wet age-related macular degeneration, a chronic eye disease.
  • The confirmatory study, called ALVOEYE, is expected to enroll about 444 participants globally.
  • The main goal of the study will be the change in visual impairment in the participants at week 8 of the trial.
  • Regeneron's Eylea brought in U.S. net sales of $1.52B in Q1 2022, a 13% Y/Y growth.
  • ALVO stock closed -2.8% at $8.50 on Wednesday.

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