Context Therapeutics, Menarini to collaborate on breast cancer treatment combo trial

Aug. 02, 2022 9:29 AM ETContext Therapeutics Inc. (CNTX)By: Anuron Mitra, SA News Editor

Love, Health Care, Donation and Charity Concept. Breast Cancer Awareness. World Cancer Survivor Day


  • Context Therapeutics (NASDAQ:CNTX) and Italian pharmaceutical major Menarini Group have entered into a clinical trial collaboration and supply agreement to evaluate a breast cancer combination treatment, the companies said on Tuesday.
  • The agreement will support the upcoming phase 1b/2 ELONA clinical trial evaluating CNTX's oral progesterone receptor (PR) antagonist ONA-XR in combination with Menarini's elacestrant in estrogen receptor positive, PR+ HER2- metastatic breast cancer patients who have previously been treated with a CDK4/6 inhibitor.
  • Context (CNTX) will sponsor the trial while Menarini will supply elacestrant at no cost.
  • CNTX said it anticipates starting the phase 1b/2 trial in Q4 this year.
  • CNTX stock gained 5.8% to $2 in premarket trading.

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