• Wed, Feb. 8, 11:47 AM
    • The buyout rumor-stoked money flow into TESARO (TSRO +7.8%) has rippled out to Clovis Oncology (CLVS +4.4%).
    • TESARO's lead oncology candidate is PARP inhibitor niraparib. Clovis' PARP inhibitor rucaparib, branded as Rubraca, was approved by the FDA two months ago.
    Wed, Feb. 8, 11:47 AM | 7 Comments
  • Sep. 20, 2016, 4:59 PM
    • Clovis (NASDAQ:CLVS) has always been considered an acquisition target with a “long list” of potential suitors including Eli Lilly (NYSE:LLY), Merck & Co. (NYSE:MRK) , and Roche, Janney tells Bloomberg in an interview.
    • CEO Patrick Mahaffy has sold other companies including Pharmion, NeXstar Pharmaceuticals.
    • Clovis closed +12.7% and is up another 7.7% AH. Earlier today the stock jumped when Gilead (NASDAQ:GILD) said it is looking for cancer deals.
    • Clovis's PDUFA date  for ovarian cancer drug rucaparib is Feb. 23, 2017.
    Sep. 20, 2016, 4:59 PM | 19 Comments
  • Mar. 20, 2015, 1:02 PM
    • According to Bloomberg, AstraZeneca's (AZN +2.6%) previously stated plan to increase revenue 75% by 2023 is looking a bit wobbly. In cancer, for example, it trails three competitors in immunotherapies for lung cancer. The FDA approved Bristol-Myers Squibb's (BMY +0.2%) Opdivo for the indication on March 4. AZN's candidate, MEDI4736, is still in clinical development with an NDA filing on tap for next year. Being late to the party means modest sales unless there is a profound advantage, something that MEDI4736 may not have unless combined with other drugs.
    • If the company's sales growth fails to ramp, its valuation could slump and encourage another takeover bid. AZN currently sports a P/E of 79 versus the industry average of 25 (per msn money).
    • Last year, CEO Pascal Soriot fought off a $117B bid from Pfizer (PFE +0.2%) telling investors that the firm could increase revenues to $45B by 2023. The company remains bullish, though. Spokesperson Esra Erkal-Paler says that the firm is making significant progress and that oncology drugs could represent 25% of sales by 2023, up from 12% in 2014. It is currently running clinical studies of AZD9291, a non-immune therapy, in lung cancer patients with a specific mutation who have relapsed after prior treatment. If it can beat rival Clovis Oncology (CLVS -2.4%) to the market, it could be worth as much as $3B per year.
    • Mirabaud analyst Nick Turner says that even if all the drugs in the pipeline make it to the market, AZN will have to stretch to reach $45B in 2023 because two of its biggest sellers, Crestor (ttm sales=$5.5B) and Nexium (ttm sales=$3.7B), face declining sales from the loss of patent protection.
    Mar. 20, 2015, 1:02 PM | 2 Comments
  • Sep. 17, 2013, 3:15 PM
    • The rally in Clovis Oncology (CLVS +5.9%) seems to be fading a bit after the stock jumped nearly 18% on a Bloomberg report which suggested the company may be pursuing a sale.
    • Worth watching on the news is Ariad (ARIA +3.6%), which rallied when the story broke. ARIA's AP26113 is an ALK, EGFR, and ROS1 inhibitor. CLVS' lead compound CO-1686 is also an EGFR inhibitor.
    • Likewise getting a bump around the time the news hit was Tesaro (TSRO +0.2%), whose Niraparib is (like CLVS' Rucapari) a PARP inhibitor.
    • Another notable company with a PARP inhibitor: BMRN, which is itself no stranger to acquisition rumors.
    Sep. 17, 2013, 3:15 PM
  • Sep. 17, 2013, 2:15 PM
    • Shares of Clovis Oncology (CLVS +13.1%) spike midday on reports the company may be exploring a sale.
    • Credit Suisse is advising the company on its options, Bloomberg says, citing sources.
    Sep. 17, 2013, 2:15 PM